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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TWM
776
Tripletail Wealth Management
Florida
$3.98K
TFA
777
Toth Financial Advisory
Virginia
$3.98K
HIA
778
HFM Investment Advisors
New Jersey
$3.98K
HPWM
779
High Point Wealth Management
New Jersey
$3.98K
AG
780
AmeriFlex Group
Nevada
$3.58K
GBT
781
Grove Bank & Trust
Florida
$3.58K
BHWM
782
Bay Harbor Wealth Management
Maryland
$3.58K
WTA
783
Washington Trust Advisors
Massachusetts
$3.42K
DPW
784
DiNuzzo Private Wealth
Pennsylvania
$3.18K
FPF
785
First Pacific Financial
Washington
$3.18K
NS
786
NBC Securities
Alabama
$3.18K
HWP
787
Highline Wealth Partners
California
$3.18K
SRCM
788
Signature Resources Capital Management
California
$3.18K
PCM
789
Penserra Capital Management
California
$3K
JFGIW
790
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$2.78K
FRA
791
Front Row Advisors
California
$2.78K
CHC
792
City Holding Co
West Virginia
$2.78K
AF
793
Advisornet Financial
Minnesota
$2.39K
PWA
794
Principia Wealth Advisory
Texas
$2.39K
SEP
795
Signature Equity Partners
Ohio
$2.39K
EWP
796
Elevation Wealth Partners
California
$2.39K
SGK
797
Steigerwald Gordon & Koch
Virginia
$2.39K
ANBT
798
American National Bank & Trust
Texas
$2.39K
WCM
799
Winthrop Capital Management
Indiana
$2K
CI
800
CX Institutional
Indiana
$2K