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Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
SRCM
776
Signature Resources Capital Management
California
$3.18K
PCM
777
Penserra Capital Management
California
$3K
JFGIW
778
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$2.78K
FRA
779
Front Row Advisors
California
$2.78K
CHC
780
City Holding Co
West Virginia
$2.78K
AF
781
Advisornet Financial
Minnesota
$2.39K
PWA
782
Principia Wealth Advisory
Texas
$2.39K
SEP
783
Signature Equity Partners
Ohio
$2.39K
SGK
784
Steigerwald Gordon & Koch
Virginia
$2.39K
EWP
785
Elevation Wealth Partners
California
$2.39K
ANBT
786
American National Bank & Trust
Texas
$2.39K
WCM
787
Winthrop Capital Management
Indiana
$2K
CI
788
CX Institutional
Indiana
$2K
ADL
789
Asset Dedication LLC
California
$1.99K
CIAS
790
CBIZ Investment Advisory Services
Ohio
$1.99K
HNW
791
High Note Wealth
Minnesota
$1.99K
LWM
792
Lodestone Wealth Management
Washington
$1.99K
DF
793
Dunhill Financial
United Kingdom
$1.99K
NRG
794
Nemes Rush Group
Michigan
$1.99K
OC
795
Optima Capital
Oregon
$1.99K
MA
796
Montag & Associates
Georgia
$1.86K
AWM
797
Abound Wealth Management
Tennessee
$1.73K
WW
798
Winnow Wealth
Texas
$1.59K
GWS
799
Greykasell Wealth Strategies
California
$1.59K
ACA
800
American Capital Advisory
Idaho
$1.59K