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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TH
751
TCTC Holdings
Texas
$7.55K
OCM
752
Osbon Capital Management
Massachusetts
$7.16K
EW
753
Elyxium Wealth
California
$7.16K
WAG
754
Wilkerson Advisory Group
Missouri
$6.76K
FDW
755
Fourth Dimension Wealth
Ohio
$6.36K
CTC
756
Cetera Trust Company
Minnesota
$6.36K
VWWMG
757
Vermillion & White Wealth Management Group
Pennsylvania
$6.36K
SAM
758
Sherman Asset Management
California
$5.96K
SS
759
Sunbelt Securities
Texas
$5.96K
SWP
760
Strategic Wealth Partners
Ohio
$5.96K
SC
761
SouthState Corp
Florida
$5.57K
TCOV
762
Trust Company of Vermont
Vermont
$5.57K
UB
763
UMB Bank
Missouri
$5.57K
HWM
764
HighMark Wealth Management
Minnesota
$5.57K
CWIG
765
Chung Wu Investment Group
Texas
$5.17K
M
766
MOTCO
Texas
$5.17K
CFM
767
Cornerstone Financial Management
Massachusetts
$5.17K
VNA
768
Valley National Advisers
Pennsylvania
$5K
ACM
769
Accent Capital Management
Ohio
$4.77K
HFS
770
Hughes Financial Services
Virginia
$4.77K
STB
771
S&T Bank
Pennsylvania
$4.37K
FHA
772
Flagship Harbor Advisors
Massachusetts
$4.37K
CW
773
Curio Wealth
Maryland
$4.01K
AIC
774
Archer Investment Corporation
Indiana
$3.98K
TWM
775
Tripletail Wealth Management
Florida
$3.98K