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Alnylam Pharmaceuticals

832 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 283 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 283 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.57B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
832
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
S
726
Sachetta
Massachusetts
$13.1K
AW
727
Avion Wealth
Texas
$13K
GGI
728
Godsey & Gibb Inc
Virginia
$12.7K
FIM
729
FWL Investment Management
Texas
$12.3K
WA
730
WPG Advisers
Maryland
$12.3K
DWM
731
Dogwood Wealth Management
Kansas
$12.3K
SR
732
Swiss Re
Switzerland
$11.9K
PTC
733
Private Trust Company
Ohio
$11.1K
PWA
734
Physician Wealth Advisors
Utah
$9.54K
SL
735
Salomon & Ludwin
Virginia
$9.15K
PG
736
Proffitt & Goodson
Tennessee
$9.15K
TCM
737
TD Capital Management
Tennessee
$9.15K
AA
738
Ancora Advisors
Ohio
$8.75K
CH
739
Cromwell Holdings
Wyoming
$7.95K
AFC
740
Ares Financial Consulting
California
$7.95K
TH
741
TCTC Holdings
Texas
$7.55K
EW
742
Elyxium Wealth
California
$7.16K
WAG
743
Wilkerson Advisory Group
Missouri
$6.76K
FDW
744
Fourth Dimension Wealth
Ohio
$6.36K
CTC
745
Cetera Trust Company
Minnesota
$6.36K
VWWMG
746
Vermillion & White Wealth Management Group
Pennsylvania
$6.36K
SAM
747
Sherman Asset Management
California
$5.96K
SS
748
Sunbelt Securities
Texas
$5.96K
SC
749
SouthState Corp
Florida
$5.57K
TCOV
750
Trust Company of Vermont
Vermont
$5.57K