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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

618 hedge funds and large institutions have $34.2B invested in Alnylam Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 108 funds opening new positions, 236 increasing their positions, 197 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
618
Holders Change
+33
Holders Change %
+5.64%
% of All Funds
8.4%
Holding in Top 10
10
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+150%
% of All Funds
0.14%
New
108
Increased
236
Reduced
197
Closed
67
Calls
$274M
Puts
$238M
Net Calls
+$35.4M
Net Calls Change
+$6.38M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$4.13B
2
Bank of America
Bank of America
North Carolina
$287M
3
Invesco
Invesco
Georgia
$247M
4
Vanguard Group
Vanguard Group
Pennsylvania
$3.53B
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$81.2M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$705M
2
Capital International Investors
Capital International Investors
California
$0
3
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$988M
4
BlackRock
BlackRock
New York
$2.58B
5
Corient Private Wealth
Corient Private Wealth
Florida
$11.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
UBS Group
51
UBS Group
Switzerland
$75.2M -$3.06M -11,328 -4%
SEI Investments
52
SEI Investments
Pennsylvania
$74.9M +$3.07M +11,369 +4%
Two Sigma Advisers
53
Two Sigma Advisers
New York
$74.5M +$53.2M +197,000 +250%
Raymond James Financial
54
Raymond James Financial
Florida
$72.6M -$2.3M -8,516 -3%
Marshall Wace
55
Marshall Wace
United Kingdom
$72.6M -$29.6M -109,717 -29%
Federated Hermes
56
Federated Hermes
Pennsylvania
$71.3M +$3.94M +14,582 +6%
Allspring Global Investments
57
Allspring Global Investments
North Carolina
$69.3M +$69.3M +270,924 New
CS
58
Candriam SCA
Luxembourg
$67.5M -$8.77M -32,488 -12%
Allianz Asset Management
59
Allianz Asset Management
Germany
$59M +$29.6M +109,632 +101%
Aberdeen Group
60
Aberdeen Group
United Kingdom
$57.1M +$6.5M +24,544 +13%
California Public Employees Retirement System
61
California Public Employees Retirement System
California
$54.4M -$716K -2,651 -1%
California State Teachers Retirement System (CalSTRS)
62
California State Teachers Retirement System (CalSTRS)
California
$53.3M +$292K +1,081 +0.6%
Two Sigma Investments
63
Two Sigma Investments
New York
$53.3M +$24.4M +90,298 +84%
Citigroup
64
Citigroup
New York
$52.6M +$29.1M +107,837 +124%
Westfield Capital Management
65
Westfield Capital Management
Massachusetts
$51.9M -$6.47M -23,954 -11%
WorldQuant Millennium Advisors
66
WorldQuant Millennium Advisors
New York
$51.6M +$11M +40,914 +27%
RhumbLine Advisers
67
RhumbLine Advisers
Massachusetts
$49M +$509K +1,885 +1%
Janus Henderson Group
68
Janus Henderson Group
United Kingdom
$48.8M -$7.63M -28,431 -14%
First Trust Advisors
69
First Trust Advisors
Illinois
$48.7M -$39.8M -147,322 -45%
SI
70
Sofinnova Investments
California
$47.6M +$17.8M +66,024 +60%
National Pension Service
71
National Pension Service
South Korea
$46.9M +$3.82M +14,148 +9%
Prudential Financial
72
Prudential Financial
New Jersey
$46.4M +$41.4M +153,253 +817%
SCM
73
SCS Capital Management
Massachusetts
$46.2M +$46.2M +171,077 New
CIBC Private Wealth Group
74
CIBC Private Wealth Group
Georgia
$46.1M +$481K +2,143 +1%
EAM
75
Eventide Asset Management
Massachusetts
$44.9M -$20M -73,968 -31%
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