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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TFM
701
TFC Financial Management
Massachusetts
$28.6K
GSWM
702
Golden State Wealth Management
California
$28.6K
WT
703
Whittier Trust
California
$28K
HPC
704
HM Payson & Co
Maine
$27K
MCM
705
MV Capital Management
Maryland
$25.1K
C
706
Covestor
United Kingdom
$25K
PWMG
707
Private Wealth Management Group
New Jersey
$24.7K
RFP
708
Root Financial Partners
California
$24.7K
TC
709
Truvestments Capital
Florida
$23.9K
GTAM
710
Global Trust Asset Management
Florida
$23.9K
CFO
711
CVA Family Office
Colorado
$23.5K
SIS
712
Sound Income Strategies
Florida
$21.9K
KAS
713
Kemnay Advisory Services
New York
$20.7K
RIAS
714
Rachor Investment Advisory Services
Michigan
$20.3K
GAM
715
Generali Asset Management
Italy
$19.9K
SJIM
716
St. Johns Investment Management
Florida
$19.9K
PFSC
717
Peoples Financial Services Corp
Pennsylvania
$19.9K
PSB
718
Piscataqua Savings Bank
New Hampshire
$19.9K
PWPS
719
Pinnacle Wealth Planning Services
Ohio
$19.3K
JWA
720
JFS Wealth Advisors
Pennsylvania
$17.9K
PWAM
721
Private Wealth Asset Management
Iowa
$16.7K
MB
722
MidFirst Bank
Oklahoma
$16.3K
MEG
723
Millstone Evans Group
Colorado
$15.9K
APW
724
Aventura Private Wealth
Florida
$15.9K
CIA
725
Cape Investment Advisory
Georgia
$15.5K