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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
MCM
701
Manchester Capital Management
Vermont
$33.4K
WTC
702
WhitTier Trust Company
Nevada
$33.3K
CPG
703
Cornerstone Planning Group
New Jersey
$33.2K
HNB
704
Hilltop National Bank
Wyoming
$31.8K
OP
705
ORG Partners
Indiana
$29K
TFM
706
TFC Financial Management
Massachusetts
$28.6K
GSWM
707
Golden State Wealth Management
California
$28.6K
WT
708
Whittier Trust
California
$28K
HPC
709
HM Payson & Co
Maine
$27K
MCM
710
MV Capital Management
Maryland
$25.1K
C
711
Covestor
United Kingdom
$25K
PWMG
712
Private Wealth Management Group
New Jersey
$24.7K
RFP
713
Root Financial Partners
California
$24.7K
TC
714
Truvestments Capital
Florida
$23.9K
GTAM
715
Global Trust Asset Management
Florida
$23.9K
CFO
716
CVA Family Office
Colorado
$23.5K
SIS
717
Sound Income Strategies
Florida
$21.9K
KAS
718
Kemnay Advisory Services
New York
$20.7K
RIAS
719
Rachor Investment Advisory Services
Michigan
$20.3K
GAM
720
Generali Asset Management
Italy
$19.9K
SJIM
721
St. Johns Investment Management
Florida
$19.9K
PSB
722
Piscataqua Savings Bank
New Hampshire
$19.9K
PFSC
723
Peoples Financial Services Corp
Pennsylvania
$19.9K
PWPS
724
Pinnacle Wealth Planning Services
Ohio
$19.3K
JWA
725
JFS Wealth Advisors
Pennsylvania
$17.9K