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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
HPC
701
HM Payson & Co
Maine
$27K
MCM
702
MV Capital Management
Maryland
$25.1K
C
703
Covestor
United Kingdom
$25K
PWMG
704
Private Wealth Management Group
New Jersey
$24.7K
RFP
705
Root Financial Partners
California
$24.7K
TC
706
Truvestments Capital
Florida
$23.9K
GTAM
707
Global Trust Asset Management
Florida
$23.9K
CFO
708
CVA Family Office
Colorado
$23.5K
SIS
709
Sound Income Strategies
Florida
$21.9K
KAS
710
Kemnay Advisory Services
New York
$20.7K
RIAS
711
Rachor Investment Advisory Services
Michigan
$20.3K
GAM
712
Generali Asset Management
Italy
$19.9K
SJIM
713
St. Johns Investment Management
Florida
$19.9K
PFSC
714
Peoples Financial Services Corp
Pennsylvania
$19.9K
PSB
715
Piscataqua Savings Bank
New Hampshire
$19.9K
PWPS
716
Pinnacle Wealth Planning Services
Ohio
$19.3K
JWA
717
JFS Wealth Advisors
Pennsylvania
$17.9K
PWAM
718
Private Wealth Asset Management
Iowa
$16.7K
MB
719
MidFirst Bank
Oklahoma
$16.3K
APW
720
Aventura Private Wealth
Florida
$15.9K
MEG
721
Millstone Evans Group
Colorado
$15.9K
CIA
722
Cape Investment Advisory
Georgia
$15.5K
BIA
723
Bell Investment Advisors
California
$14.3K
SWA
724
SOA Wealth Advisors
New York
$14.3K
BWL
725
Bogart Wealth LLC
Virginia
$14.3K