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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
CA
676
Clearstead Advisors
Ohio
$58.5K
SS
677
SBI Securities
Japan
$58.5K
ZBNA
678
Zions Bancorporation, National Association
Utah
$58.5K
QL
679
Quarry LP
New York
$57.3K
IUHSA
680
Itau Unibanco Holding S.A.
Brazil
$56.1K
SC
681
Steph & Co
Wisconsin
$53.7K
BLC
682
Brown, Lisle/Cummings
Rhode Island
$52.5K
Fifth Third Bancorp
683
Fifth Third Bancorp
Ohio
$50.5K
PPC
684
Park Place Capital
Alabama
$50.1K
FAMI
685
Fideuram Asset Management (Ireland)
$49.8K
RF
686
Rossby Financial
Florida
$49.3K
HI
687
Harbour Investments
Wisconsin
$46.1K
SWM
688
SHP Wealth Management
Massachusetts
$43.2K
AWM
689
Activest Wealth Management
Florida
$42.9K
TW
690
Titan Wealth
$41.8K
LSA
691
Leonteq Securities AG
Switzerland
$41.8K
EB
692
Eastern Bank
Massachusetts
$41.8K
KFAS
693
Keating Financial Advisory Services
Kansas
$41.4K
HNB
694
Huntington National Bank
Ohio
$40.6K
HFM
695
Hartford Financial Management
Connecticut
$39.8K
CT
696
Colonial Trust
South Carolina
$39.4K
PFBT
697
Parkside Financial Bank & Trust
Missouri
$38.6K
EC
698
Elequin Capital
New York
$38.6K
WIM
699
Westside Investment Management
California
$38.4K
QC
700
Quent Capital
New York
$37.4K