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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
GWM
651
Greenline Wealth Management
Florida
$96.1K
LFG
652
Larson Financial Group
Missouri
$95.8K
TM
653
Torren Management
California
$93.4K
AUB
654
Atlantic Union Bankshares
Virginia
$91.9K
Bessemer Group
655
Bessemer Group
New Jersey
$90K
SSG
656
Summit Securities Group
New York
$80.3K
SWM
657
Spire Wealth Management
Virginia
$80.3K
CWP
658
Concord Wealth Partners
Virginia
$79.5K
MPWT
659
MassMutual Private Wealth & Trust
Connecticut
$77.1K
LI
660
LRI Investments
Florida
$76.2K
RS
661
Rakuten Securities
Japan
$75.2K
BBHC
662
Brown Brothers Harriman & Co
New York
$71.6K
EPIM
663
Evelyn Partners Investment Management
$69.6K
PWMG
664
Prestige Wealth Management Group
New Jersey
$68.8K
FHC
665
First Horizon Corporation
Tennessee
$64.8K
CAL
666
Capital Advisors Ltd
Ohio
$64K
RAM
667
Reflection Asset Management
South Carolina
$63.2K
TWD
668
True Wealth Design
Ohio
$61.5K
MAM
669
Meeder Asset Management
Ohio
$61.2K
CA
670
CoreCap Advisors
Michigan
$60.4K
CA
671
Clearstead Advisors
Ohio
$58.5K
SS
672
SBI Securities
Japan
$58.5K
ZBNA
673
Zions Bancorporation, National Association
Utah
$58.5K
QL
674
Quarry LP
New York
$57.3K
IUHSA
675
Itau Unibanco Holding S.A.
Brazil
$56.1K