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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
LFG
651
Larson Financial Group
Missouri
$95.8K
TM
652
Torren Management
California
$93.4K
AUB
653
Atlantic Union Bankshares
Virginia
$91.9K
Bessemer Group
654
Bessemer Group
New Jersey
$90K
SSG
655
Summit Securities Group
New York
$80.3K
SWM
656
Spire Wealth Management
Virginia
$80.3K
CWP
657
Concord Wealth Partners
Virginia
$79.5K
MPWT
658
MassMutual Private Wealth & Trust
Connecticut
$77.1K
LI
659
LRI Investments
Florida
$76.2K
RS
660
Rakuten Securities
Japan
$75.2K
BBHC
661
Brown Brothers Harriman & Co
New York
$71.6K
EPIM
662
Evelyn Partners Investment Management
$69.6K
PWMG
663
Prestige Wealth Management Group
New Jersey
$68.8K
FHC
664
First Horizon Corporation
Tennessee
$64.8K
CAL
665
Capital Advisors Ltd
Ohio
$64K
TWD
666
True Wealth Design
Ohio
$61.5K
MAM
667
Meeder Asset Management
Ohio
$61.2K
CA
668
CoreCap Advisors
Michigan
$60.4K
CA
669
Clearstead Advisors
Ohio
$58.5K
SS
670
SBI Securities
Japan
$58.5K
ZBNA
671
Zions Bancorporation, National Association
Utah
$58.5K
QL
672
Quarry LP
New York
$57.3K
IUHSA
673
Itau Unibanco Holding S.A.
Brazil
$56.1K
SC
674
Steph & Co
Wisconsin
$53.7K
BLC
675
Brown, Lisle/Cummings
Rhode Island
$52.5K