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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
EFMH
651
E Fund Management (HK)
Hong Kong
$132K
TWC
652
TD Waterhouse Canada
Ontario, Canada
$131K
HP
653
Havemeyer Place
Connecticut
$119K
BTI
654
Blue Trust Inc
Georgia
$113K
MR
655
Munich Reinsurance
$109K
GWM
656
Greenline Wealth Management
Florida
$96.1K
LFG
657
Larson Financial Group
Missouri
$95.8K
TM
658
Torren Management
California
$93.4K
AUB
659
Atlantic Union Bankshares
Virginia
$91.9K
Bessemer Group
660
Bessemer Group
New Jersey
$90K
SSG
661
Summit Securities Group
New York
$80.3K
SWM
662
Spire Wealth Management
Virginia
$80.3K
CWP
663
Concord Wealth Partners
Virginia
$79.5K
MPWT
664
MassMutual Private Wealth & Trust
Connecticut
$77.1K
LI
665
LRI Investments
Florida
$76.2K
RS
666
Rakuten Securities
Japan
$75.2K
BBHC
667
Brown Brothers Harriman & Co
New York
$71.6K
EPIM
668
Evelyn Partners Investment Management
$69.6K
PWMG
669
Prestige Wealth Management Group
New Jersey
$68.8K
FHC
670
First Horizon Corporation
Tennessee
$64.8K
CAL
671
Capital Advisors Ltd
Ohio
$64K
RAM
672
Reflection Asset Management
South Carolina
$63.2K
TWD
673
True Wealth Design
Ohio
$61.5K
MAM
674
Meeder Asset Management
Ohio
$61.2K
CA
675
CoreCap Advisors
Michigan
$60.4K