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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
PWG
626
Portside Wealth Group
Utah
$217K
EL
627
Essex LLC
Illinois
$217K
CPA
628
Capital Performance Advisors
California
$215K
FFA
629
Fi3 Financial Advisors
Indiana
$214K
IB
630
Intrust Bank
Kansas
$214K
TFIPS
631
Towarzystwo Funduszy Inwestycyjnych PZU SA
$211K
SIA
632
Soltis Investment Advisors
Utah
$211K
AC
633
AlphaCore Capital
California
$210K
AWM
634
Ariadne Wealth Management
California
$209K
GS
635
GTS Securities
New York
$209K
CFP
636
Cascade Financial Partners
California
$208K
FFO
637
Fortitude Family Office
Arizona
$206K
OIA
638
OneDigital Investment Advisors
Kansas
$203K
PA
639
PharVision Advisers
Florida
$200K
PCTC
640
Perkins Coie Trust Company
Washington
$199K
HI
641
Horizon Investments
North Carolina
$179K
MCM
642
MAI Capital Management
Ohio
$178K
EPL
643
Essential Partners LLC
California
$177K
UFF
644
USA Financial Formulas
Michigan
$169K
VCM
645
Versant Capital Management
Arizona
$165K
BC
646
Bayforest Capital
United Kingdom
$164K
SAG
647
SageView Advisory Group
California
$158K
RIL
648
Rothschild Investment LLC
Illinois
$143K
QT
649
Quantbot Technologies
New York
$139K
GC
650
Globeflex Capital
California
$133K