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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
JRPIM
601
Journey Retirement Planning & Investment Management
Idaho
$251K
EW
602
Evoke Wealth
California
$247K
TCA
603
Transcend Capital Advisors
New Jersey
$247K
EA
604
Everpar Advisors
Oklahoma
$247K
QCG
605
Quadrant Capital Group
Ohio
$245K
IAA
606
Independent Advisor Alliance
North Carolina
$241K
WC
607
Waterloo Capital
Texas
$241K
PE
608
PCM Encore
Colorado
$240K
CP
609
Covenant Partners
Tennessee
$240K
LWM
610
LeConte Wealth Management
Tennessee
$240K
AG
611
AlTi Global
New York
$239K
EWM
612
Evercore Wealth Management
New York
$239K
PPWP
613
Premier Path Wealth Partners
New Jersey
$237K
GCM
614
Graham Capital Management
Connecticut
$234K
LA
615
LVW Advisors
New York
$231K
Northwestern Mutual Wealth Management
616
Northwestern Mutual Wealth Management
Wisconsin
$231K
AG
617
Algert Global
California
$231K
CFG
618
Cooper Financial Group
California
$231K
KWA
619
Kingswood Wealth Advisors
California
$228K
OCBCO
620
Oversea-Chinese Banking Corp (OCBC)
Singapore
$225K
NWM
621
Northwest Wealth Management
Iowa
$225K
FCP
622
Fidelis Capital Partners
Florida
$224K
AA
623
Alta Advisers
United Kingdom
$221K
CPIG
624
Chicago Partners Investment Group
Illinois
$221K
GF
625
Gabelli Funds
New York
$219K