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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
GI
551
GAMMA Investing
California
$355K
BFIM
552
Beese Fulmer Investment Management
Ohio
$353K
SC
553
Savant Capital
Illinois
$348K
EI
554
Ellevest Inc
New York
$343K
JTWM
555
Jackson Thornton Wealth Management
Alabama
$342K
PAG
556
Poinciana Advisors Group
Florida
$338K
SI
557
Stephens Inc
Arkansas
$336K
WA
558
Waverly Advisors
Alabama
$334K
SCA
559
Snowden Capital Advisors
New York
$332K
MOS
560
MGO One Seven
Ohio
$331K
HAG
561
HighPoint Advisor Group
Illinois
$331K
NL
562
NWAM LLC
Washington
$330K
PA
563
Parallel Advisors
California
$329K
CD
564
Chapin Davis
Maryland
$328K
CPC
565
Cookson Peirce & Co
Pennsylvania
$322K
CIA
566
Concurrent Investment Advisors
Florida
$319K
AG
567
Ascent Group
Virginia
$316K
BAM
568
Blueshift Asset Management
New Jersey
$315K
BPA
569
Beacon Pointe Advisors
California
$314K
Lido Advisors
570
Lido Advisors
California
$312K
Jones Financial Companies
571
Jones Financial Companies
Missouri
$310K
PWM
572
Perigon Wealth Management
California
$309K
WCP
573
Wick Capital Partners
Pennsylvania
$306K
SW
574
SkyOak Wealth
Michigan
$302K
KRW
575
Kaufman Rossin Wealth
Florida
$298K