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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
EI
551
Ellevest Inc
New York
$343K
JTWM
552
Jackson Thornton Wealth Management
Alabama
$342K
PAG
553
Poinciana Advisors Group
Florida
$338K
SI
554
Stephens Inc
Arkansas
$336K
WA
555
Waverly Advisors
Alabama
$334K
SCA
556
Snowden Capital Advisors
New York
$332K
MOS
557
MGO One Seven
Ohio
$331K
HAG
558
HighPoint Advisor Group
Illinois
$331K
NL
559
NWAM LLC
Washington
$330K
PA
560
Parallel Advisors
California
$329K
CD
561
Chapin Davis
Maryland
$328K
CPC
562
Cookson Peirce & Co
Pennsylvania
$322K
CIA
563
Concurrent Investment Advisors
Florida
$319K
AG
564
Ascent Group
Virginia
$316K
BAM
565
Blueshift Asset Management
New Jersey
$315K
BPA
566
Beacon Pointe Advisors
California
$314K
Lido Advisors
567
Lido Advisors
California
$312K
Jones Financial Companies
568
Jones Financial Companies
Missouri
$310K
PWM
569
Perigon Wealth Management
California
$309K
WCP
570
Wick Capital Partners
Pennsylvania
$306K
SW
571
SkyOak Wealth
Michigan
$302K
KRW
572
Kaufman Rossin Wealth
Florida
$298K
BEI
573
Benjamin Edwards Inc
Missouri
$291K
BS
574
Banco Santander
Spain
$291K
SFC
575
SYM Financial Corp
Indiana
$290K