ALNY icon

Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
FFM
476
Forum Financial Management
Illinois
$615K
OCM
477
Orser Capital Management
Texas
$612K
EC
478
EntryPoint Capital
New York
$607K
VT
479
Vise Technologies
New York
$602K
HNWAG
480
High Net Worth Advisory Group
Florida
$596K
YCM
481
Yousif Capital Management
Michigan
$596K
SW
482
SteelPeak Wealth
California
$590K
QI
483
Qtron Investments
Massachusetts
$585K
SF
484
Summit Financial
New Jersey
$579K
1C
485
111 Capital
France
$577K
KF
486
Krilogy Financial
Missouri
$573K
PAP
487
Persistent Asset Partners
Hong Kong
$570K
FB
488
Fulton Bank
Pennsylvania
$569K
SPIA
489
Steward Partners Investment Advisory
New York
$567K
SFA
490
Souders Financial Advisors
Ohio
$561K
LJAC
491
L.J. Altfest & Co
New York
$548K
LWCFA
492
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$544K
AF
493
Allworth Financial
California
$538K
HT
494
Headlands Technologies
Illinois
$535K
PR
495
PSP Research
Pennsylvania
$524K
WAP
496
Wealthcare Advisory Partners
Pennsylvania
$521K
AA
497
AlphaCentric Advisors
Puerto Rico
$515K
SI
498
Sava Infond
Slovenia
$511K
SBFM
499
S-Bank Fund Management
Finland
$509K
CGH
500
Crossmark Global Holdings
Texas
$509K