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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
OCM
476
Orser Capital Management
Texas
$612K
EC
477
EntryPoint Capital
New York
$607K
VT
478
Vise Technologies
New York
$602K
HNWAG
479
High Net Worth Advisory Group
Florida
$596K
YCM
480
Yousif Capital Management
Michigan
$596K
SW
481
SteelPeak Wealth
California
$590K
QI
482
Qtron Investments
Massachusetts
$585K
SF
483
Summit Financial
New Jersey
$579K
1C
484
111 Capital
France
$577K
KF
485
Krilogy Financial
Missouri
$573K
PAP
486
Persistent Asset Partners
Hong Kong
$570K
FB
487
Fulton Bank
Pennsylvania
$569K
SPIA
488
Steward Partners Investment Advisory
New York
$567K
SFA
489
Souders Financial Advisors
Ohio
$561K
LJAC
490
L.J. Altfest & Co
New York
$548K
LWCFA
491
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$544K
AF
492
Allworth Financial
California
$538K
HT
493
Headlands Technologies
Illinois
$535K
PR
494
PSP Research
Pennsylvania
$524K
WAP
495
Wealthcare Advisory Partners
Pennsylvania
$521K
AA
496
AlphaCentric Advisors
Puerto Rico
$515K
SI
497
Sava Infond
Slovenia
$511K
SBFM
498
S-Bank Fund Management
Finland
$509K
CGH
499
Crossmark Global Holdings
Texas
$509K
Winslow Capital Management
500
Winslow Capital Management
Minnesota
$503K