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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
CCM
476
Coldstream Capital Management
Washington
$626K
DT
477
Diversified Trust
Tennessee
$616K
FFM
478
Forum Financial Management
Illinois
$615K
OCM
479
Orser Capital Management
Texas
$612K
EC
480
EntryPoint Capital
New York
$607K
VT
481
Vise Technologies
New York
$602K
HNWAG
482
High Net Worth Advisory Group
Florida
$596K
YCM
483
Yousif Capital Management
Michigan
$596K
SW
484
SteelPeak Wealth
California
$590K
QI
485
Qtron Investments
Massachusetts
$585K
SF
486
Summit Financial
New Jersey
$579K
1C
487
111 Capital
France
$577K
KF
488
Krilogy Financial
Missouri
$573K
PAP
489
Persistent Asset Partners
Hong Kong
$570K
FB
490
Fulton Bank
Pennsylvania
$569K
SPIA
491
Steward Partners Investment Advisory
New York
$567K
SFA
492
Souders Financial Advisors
Ohio
$561K
LJAC
493
L.J. Altfest & Co
New York
$548K
LWCFA
494
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$544K
AF
495
Allworth Financial
California
$538K
HT
496
Headlands Technologies
Illinois
$535K
PR
497
PSP Research
Pennsylvania
$524K
WAP
498
Wealthcare Advisory Partners
Pennsylvania
$521K
AA
499
AlphaCentric Advisors
Puerto Rico
$515K
SI
500
Sava Infond
Slovenia
$511K