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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

618 hedge funds and large institutions have $34.2B invested in Alnylam Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 108 funds opening new positions, 236 increasing their positions, 197 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
618
Holders Change
+33
Holders Change %
+5.64%
% of All Funds
8.4%
Holding in Top 10
10
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+150%
% of All Funds
0.14%
New
108
Increased
236
Reduced
197
Closed
67
Calls
$274M
Puts
$238M
Net Calls
+$35.4M
Net Calls Change
+$6.38M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$4.13B
2
Bank of America
Bank of America
North Carolina
$287M
3
Invesco
Invesco
Georgia
$247M
4
Vanguard Group
Vanguard Group
Pennsylvania
$3.53B
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$81.2M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$705M
2
Capital International Investors
Capital International Investors
California
$0
3
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$988M
4
BlackRock
BlackRock
New York
$2.58B
5
Corient Private Wealth
Corient Private Wealth
Florida
$11.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
Deutsche Bank
26
Deutsche Bank
Germany
$156M +$5.51M +20,414 +4%
Charles Schwab
27
Charles Schwab
California
$150M +$11M +40,644 +8%
NL
28
Nuveen LLC
North Carolina
$149M +$149M +883,374 New
Loomis, Sayles & Company
29
Loomis, Sayles & Company
Massachusetts
$134M -$1.5M -5,561 -1%
TD Asset Management
30
TD Asset Management
Ontario, Canada
$131M -$4.71M -17,454 -3%
Pictet Asset Management
31
Pictet Asset Management
Switzerland
$130M +$13.6M +50,355 +12%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$128M -$1.18M -4,371 -0.9%
Franklin Resources
33
Franklin Resources
California
$124M +$11.9M +44,175 +11%
Amundi
34
Amundi
France
$119M -$10.8M -41,306 -8%
Goldman Sachs
35
Goldman Sachs
New York
$114M +$31.6M +116,912 +38%
Swiss National Bank
36
Swiss National Bank
Switzerland
$98.3M +$432K +1,600 +0.4%
O
37
OrbiMed
New York
$93.5M -$18.8M -69,500 -17%
GGHC
38
Gilder Gagnon Howe & Co
New York
$93.3M -$5.37M -19,888 -5%
Royal Bank of Canada
39
Royal Bank of Canada
Ontario, Canada
$91.1M +$7.3M +27,044 +9%
Qube Research & Technologies (QRT)
40
Qube Research & Technologies (QRT)
United Kingdom
$89.2M -$41.8M -154,913 -32%
Dimensional Fund Advisors
41
Dimensional Fund Advisors
Texas
$83.6M -$6.44M -23,842 -7%
Jennison Associates
42
Jennison Associates
New York
$83.5M +$13.3M +49,306 +19%
Point72 Asset Management
43
Point72 Asset Management
Connecticut
$81.2M +$81.2M +300,635 New
Wells Fargo
44
Wells Fargo
California
$81M +$6.24M +23,118 +8%
Sumitomo Mitsui Trust Group
45
Sumitomo Mitsui Trust Group
Japan
$78.7M +$1.29M +4,773 +2%
D.E. Shaw & Co
46
D.E. Shaw & Co
New York
$78.3M -$19.8M -73,223 -20%
Millennium Management
47
Millennium Management
New York
$77.6M -$12.4M -46,105 -14%
Royal London Asset Management
48
Royal London Asset Management
United Kingdom
$77.5M +$1.47M +5,434 +2%
Adage Capital Partners
49
Adage Capital Partners
Massachusetts
$76.2M +$51.1M +189,128 +203%
PCH
50
Polar Capital Holdings
United Kingdom
$75.6M -$8.1M -30,000 -10%
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