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Alnylam Pharmaceuticals

848 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 170 funds opening new positions, 289 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more call options, than puts

Call options by funds: $760M | Put options by funds: $494M

44% more first-time investments, than exits

New positions opened: 170 | Existing positions closed: 118

3% more funds holding

Funds holding: 821848 (+27)

0% less repeat investments, than reductions

Existing positions increased: 289 | Existing positions reduced: 290

0.86% less ownership

Funds ownership: 99.09%98.23% (-0.86%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.5B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
848
Holders Change
+27
Holders Change %
+3.29%
% of All Funds
10.32%
Holding in Top 10
4
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-69.23%
% of All Funds
0.05%
New
170
Increased
289
Reduced
290
Closed
118
Calls
$760M
Puts
$494M
Net Calls
+$266M
Net Calls Change
+$352M
Name Holding Trade Value Shares
Change
Change in
Stake
OAM
426
Oxford Asset Management
United Kingdom
$1.01M -$361K -816 -24%
UM
427
UniSuper Management
Australia
$994K +$133K +300 +14%
TF
428
Theory Financial
Colorado
$992K +$1.21M +2,744 New
PSC
429
Portman Square Capital
United Kingdom
$977K +$1.09M +2,457 New
UCFA
430
United Capital Financial Advisors
Texas
$974K +$135K +304 +14%
IG
431
ING Group
Netherlands
$972K +$1.08M +2,444 New
DAM
432
Draper Asset Management
New York
$963K +$743K +1,680 +226%
I
433
InceptionR
California
$960K -$489K -1,104 -31%
CPBTD
434
Central Pacific Bank - Trust Division
Hawaii
$960K -$98.2K -222 -8%
PAS
435
Park Avenue Securities
New York
$951K -$150K -340 -12%
HKAM
436
Horizon Kinetics Asset Management
New York
$945K -$46K -104 -4%
QCM
437
QRG Capital Management
Illinois
$940K -$31.9K -72 -3%
ETC
438
Exchange Traded Concepts
Oklahoma
$939K +$127K +288 +14%
NPT
439
Nixon Peabody Trust
Massachusetts
$929K -$4.43K -10 -0.4%
Vontobel Holding
440
Vontobel Holding
Switzerland
$922K -$205K -463 -17%
CCM
441
Capstone Capital Management
$915K +$1.02M +2,301 New
TCM
442
Twin Capital Management
Pennsylvania
$878K +$977K +2,208 New
PAG
443
Private Advisory Group
Washington
$857K +$326K +736 +52%
IPAM
444
ICICI Prudential Asset Management
India
$843K +$938K +2,120 New
AGM
445
Alpine Global Management
New York
$820K +$913K +2,062 New
DS
446
DRW Securities
Illinois
$812K +$903K +2,041 New
ACS
447
Archford Capital Strategies
Illinois
$805K
EPM
448
Elm Partners Management
Pennsylvania
$798K +$889K +2,008 New
SNBOSD
449
Security National Bank of So Dak
Iowa
$795K
TG
450
TCW Group
California
$795K +$885K +2,000 New