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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
NDSIB
351
North Dakota State Investment Board
North Dakota
$1.9M
AIP
352
Ameritas Investment Partners
Nebraska
$1.9M
AAM
353
Azzad Asset Management
Virginia
$1.83M
EOJOAM
354
E. Ohman J:or Asset Management
Sweden
$1.82M
BC
355
Burney Company
Virginia
$1.82M
OAC
356
OMERS Administration Corp
Ontario, Canada
$1.8M
MFG
357
Merit Financial Group
Georgia
$1.79M
NB
358
Norinchukin Bank
Japan
$1.78M
BHCM
359
Brevan Howard Capital Management
Jersey
$1.76M
BCI
360
Brinker Capital Investments
Pennsylvania
$1.75M
Envestnet Portfolio Solutions
361
Envestnet Portfolio Solutions
Illinois
$1.73M
QIM
362
Quantitative Investment Management
Virginia
$1.72M
AAM
363
Advisors Asset Management
Colorado
$1.71M
NSUP
364
NLB Skladi upravljanje premozenja
$1.71M
HHGC
365
Hunting Hill Global Capital
New York
$1.69M
HCM
366
Howland Capital Management
Massachusetts
$1.69M
IWC
367
Integrated Wealth Concepts
Massachusetts
$1.69M
SFA
368
Sequoia Financial Advisors
Ohio
$1.67M
MGP
369
Metis Global Partners
California
$1.66M
PCA
370
Pallas Capital Advisors
Massachusetts
$1.63M
FPAS
371
Focus Partners Advisor Solutions
Missouri
$1.63M
Comerica Bank
372
Comerica Bank
Texas
$1.61M
GC
373
Gilbert & Cook
Iowa
$1.6M
Verition Fund Management
374
Verition Fund Management
Connecticut
$1.59M
CT
375
Clearstead Trust
Maine
$1.58M