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Alnylam Pharmaceuticals

839 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 165 funds opening new positions, 286 increasing their positions, 289 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

1% less repeat investments, than reductions

Existing positions increased: 286 | Existing positions reduced: 289

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.51B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
839
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
AAM
351
Azzad Asset Management
Virginia
$1.83M
EOJOAM
352
E. Ohman J:or Asset Management
Sweden
$1.82M
BC
353
Burney Company
Virginia
$1.82M
OAC
354
OMERS Administration Corp
Ontario, Canada
$1.8M
MFG
355
Merit Financial Group
Georgia
$1.79M
NB
356
Norinchukin Bank
Japan
$1.78M
BHCM
357
Brevan Howard Capital Management
Jersey
$1.76M
BCI
358
Brinker Capital Investments
Pennsylvania
$1.75M
Envestnet Portfolio Solutions
359
Envestnet Portfolio Solutions
Illinois
$1.73M
QIM
360
Quantitative Investment Management
Virginia
$1.72M
AAM
361
Advisors Asset Management
Colorado
$1.71M
NSUP
362
NLB Skladi upravljanje premozenja
$1.71M
HHGC
363
Hunting Hill Global Capital
New York
$1.69M
HCM
364
Howland Capital Management
Massachusetts
$1.69M
IWC
365
Integrated Wealth Concepts
Massachusetts
$1.69M
SFA
366
Sequoia Financial Advisors
Ohio
$1.67M
MGP
367
Metis Global Partners
California
$1.66M
PCA
368
Pallas Capital Advisors
Massachusetts
$1.63M
FPAS
369
Focus Partners Advisor Solutions
Missouri
$1.63M
Comerica Bank
370
Comerica Bank
Texas
$1.61M
GC
371
Gilbert & Cook
Iowa
$1.6M
Verition Fund Management
372
Verition Fund Management
Connecticut
$1.59M
CT
373
Clearstead Trust
Maine
$1.58M
6CM
374
683 Capital Management
New York
$1.5M
FA
375
Faithward Advisors
Pennsylvania
$1.5M