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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

617 hedge funds and large institutions have $34.2B invested in Alnylam Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 107 funds opening new positions, 236 increasing their positions, 197 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
617
Holders Change
+32
Holders Change %
+5.47%
% of All Funds
8.38%
Holding in Top 10
10
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+150%
% of All Funds
0.14%
New
107
Increased
236
Reduced
197
Closed
67
Calls
$274M
Puts
$238M
Net Calls
+$35.4M
Net Calls Change
+$6.38M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$493M
2
Bank of America
Bank of America
North Carolina
+$174M
3
Invesco
Invesco
Georgia
+$95.9M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$87.3M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
+$81.2M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$428M
2
Capital International Investors
Capital International Investors
California
-$334M
3
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$103M
4
BlackRock
BlackRock
New York
-$88M
5
Corient Private Wealth
Corient Private Wealth
Florida
-$63.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
PAP
351
Persistent Asset Partners
Hong Kong
$819K +$819K +3,034 New
GD
352
Grandfield & Dodd
New York
$819K +$178K +659 +28%
ECM
353
Everence Capital Management
Indiana
$802K +$122K +450 +18%
RIA
354
Regal Investment Advisors
Michigan
$785K -$68K -252 -8%
GIC
355
Generali Investments CEE
Czech Republic
$783K – – –
HKAM
356
Horizon Kinetics Asset Management
New York
$778K – – –
KeyBank National Association
357
KeyBank National Association
Ohio
$754K -$18.4K -68 -2%
GT
358
Greenleaf Trust
Michigan
$743K +$7.56K +28 +1%
IWC
359
Integrated Wealth Concepts
Massachusetts
$740K +$61.3K +227 +9%
SFP
360
Shepherd Financial Partners
Massachusetts
$739K – – –
BWMG
361
Bannerman Wealth Management Group
Texas
$737K +$361K +1,338 +96%
SW
362
SteelPeak Wealth
California
$736K -$203K -753 -22%
FPAS
363
Focus Partners Advisor Solutions
Missouri
$736K +$503K +1,862 +216%
VA
364
Vident Advisory
Georgia
$720K +$362K +1,340 +101%
CPBTD
365
Central Pacific Bank - Trust Division
Hawaii
$716K +$445K +1,648 +164%
UM
366
UniSuper Management
Australia
$675K – – –
VI
367
Vestcor Inc
New Brunswick, Canada
$665K +$1.62K +6 +0.2%
Wolverine Trading
368
Wolverine Trading
Illinois
$655K -$1.31M -4,885 -67%
Walleye Capital
369
Walleye Capital
New York
$640K -$4.79M -17,746 -88%
EC
370
EntryPoint Capital
New York
$638K -$48.1K -178 -7%
Kovitz Investment Group Partners
371
Kovitz Investment Group Partners
Illinois
$634K -$78.8K -292 -11%
PEAK6
372
PEAK6
Illinois
$620K -$2.27M -8,407 -79%
NPT
373
Nixon Peabody Trust
Massachusetts
$615K -$4.32K -16 -0.7%
ACM
374
Aster Capital Management
United Arab Emirates
$605K +$605K +2,451 New
CI Investments Inc
375
CI Investments Inc
Ontario, Canada
$600K -$341K -1,263 -36%
13 14
15
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