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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
PIM
326
Plato Investment Management
Australia
$2.5M
DILIC
327
Dai-ichi Life Insurance Company
Japan
$2.49M
AI
328
Atria Investments
North Carolina
$2.45M
Pathstone Holdings
329
Pathstone Holdings
New Jersey
$2.44M
Truist Financial
330
Truist Financial
North Carolina
$2.43M
CI Investments Inc
331
CI Investments Inc
Ontario, Canada
$2.41M
KIM
332
Kestra Investment Management
Texas
$2.39M
BCM
333
Bridgeway Capital Management
Texas
$2.38M
Walleye Capital
334
Walleye Capital
New York
$2.37M
TRCT
335
Tower Research Capital (TRC)
New York
$2.32M
AAIS
336
ABN AMRO Investment Solutions
$2.29M
ALMGDA
337
AG2R La Mondiale Gestion d'Actifs
France
$2.22M
DP
338
Diadema Partners
New Jersey
$2.12M
WBC
339
Westpac Banking Corp
Australia
$2.11M
GCM
340
Genus Capital Management
British Columbia, Canada
$2.09M
BMSSC
341
B. Metzler seel. Sohn & Co
Germany
$2.09M
US Bancorp
342
US Bancorp
Minnesota
$2.08M
VA
343
Vident Advisory
Georgia
$2.05M
GIA
344
Gateway Investment Advisers
Ohio
$2.04M
PL
345
Perpetual Ltd
Australia
$2M
TMAM
346
Tokio Marine Asset Management
Japan
$1.99M
SPS
347
Susquehanna Portfolio Strategies
Pennsylvania
$1.99M
WMA
348
West Michigan Advisors
Michigan
$1.99M
TI
349
Tidal Investments
Wisconsin
$1.92M
A
350
AustralianSuper
Australia
$1.91M