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Alnylam Pharmaceuticals

781 hedge funds and large institutions have $42.4B invested in Alnylam Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 103 funds opening new positions, 319 increasing their positions, 254 reducing their positions, and 154 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

18% less capital invested

Capital invested by funds: $51.7B → $42.4B (-$9.26B)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

33% less first-time investments, than exits

New positions opened: 103 | Existing positions closed: 154

Holders
781
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$450M
Puts
$205M
Net Calls
Net Calls Change

Top Buyers

1 +$1.17B
2 +$916M
3 +$546M
4
Two Sigma Investments
Two Sigma Investments
New York
+$468M
5
ClearBridge Investments
ClearBridge Investments
New York
+$258M

Top Sellers

1 -$1.87B
2 -$450M
3 -$448M
4
Invesco
Invesco
Georgia
-$297M
5
1832 Asset Management
1832 Asset Management
Ontario, Canada
-$175M
Name Holding Trade Value Shares
Change
Change in
Stake
ERSOT
301
Employees Retirement System of Texas
Texas
$2.78M
KIM
302
Kestra Investment Management
Texas
$2.78M
Wealth Enhancement Advisory Services
303
Wealth Enhancement Advisory Services
Minnesota
$2.7M
M&T Bank
304
M&T Bank
New York
$2.6M
ZIM
305
Zacks Investment Management
Illinois
$2.6M
DJSG
306
D.J. St. Germain
Massachusetts
$2.6M
MIM
307
MetLife Investment Management
New Jersey
$2.58M
Bank of Nova Scotia
308
Bank of Nova Scotia
Ontario, Canada
$2.58M
AG
309
AIA Group
Hong Kong
$2.56M
Truist Financial
310
Truist Financial
North Carolina
$2.55M
PP
311
Prudential plc
United Kingdom
$2.55M
VIA
312
Virtus Investment Advisers
Connecticut
$2.47M
SCI
313
S&CO Inc
Massachusetts
$2.45M
US Bancorp
314
US Bancorp
Minnesota
$2.44M
JPMIA
315
J.P. Marvel Investment Advisors
Massachusetts
$2.35M
Pathstone Holdings
316
Pathstone Holdings
New Jersey
$2.34M
OIMU
317
Osmosis Investment Management UK
United Kingdom
$2.32M
PIMJS
318
PKO Investment Management Joint-Stock
Poland
$2.25M
LCM
319
Legato Capital Management
California
$2.16M
CGIM
320
Capital Group Investment Management
Singapore
$2.14M
VA
321
Vident Advisory
Georgia
$2.14M
Rockefeller Capital Management
322
Rockefeller Capital Management
New York
$2.13M
MSRPS
323
Maryland State Retirement & Pension System
Maryland
$2.1M
AC
324
Allstate Corporation
Illinois
$2.1M
ASN
325
Advisory Services Network
Georgia
$2.09M