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Alnylam Pharmaceuticals

848 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 170 funds opening new positions, 289 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more call options, than puts

Call options by funds: $760M | Put options by funds: $494M

44% more first-time investments, than exits

New positions opened: 170 | Existing positions closed: 118

3% more funds holding

Funds holding: 821848 (+27)

0% less repeat investments, than reductions

Existing positions increased: 289 | Existing positions reduced: 290

0.86% less ownership

Funds ownership: 99.09%98.23% (-0.86%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.5B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
848
Holders Change
+27
Holders Change %
+3.29%
% of All Funds
10.32%
Holding in Top 10
4
Holding in Top 10 Change
-9
Holding in Top 10 Change %
-69.23%
% of All Funds
0.05%
New
170
Increased
289
Reduced
290
Closed
118
Calls
$760M
Puts
$494M
Net Calls
+$266M
Net Calls Change
+$352M
Name Holding Trade Value Shares
Change
Change in
Stake
HFS
276
Hantz Financial Services
Michigan
$4.5M -$807K -1,823 -14%
KCM
277
Kornitzer Capital Management
Kansas
$4.42M -$5.57M -12,575 -53%
BCV
278
Banque Cantonale Vaudoise
Switzerland
$4.39M +$2.73M +6,177 +127%
CFB
279
Cullen/Frost Bankers
Texas
$4.39M -$4.43K -10 -0.1%
AV
280
ASR Vermogensbeheer
Netherlands
$4.38M +$950K +2,146 +24%
CWM
281
CIBC World Markets
New York
$4.36M +$4.85M +10,965 New
AB
282
Amalgamated Bank
New York
$4.25M +$237K +535 +5%
CB
283
Commerce Bank
Missouri
$4.19M +$2.66M +6,002 +132%
SAM
284
Silvercrest Asset Management
New York
$4.14M -$176K -397 -4%
ACM
285
Atika Capital Management
New York
$4.11M -$5.25M -11,867 -53%
HFM
286
Harvest Fund Management
China
$4.1M +$3.67M +8,298 +411%
HCS
287
Himension Capital (Singapore)
Singapore
$4.05M +$40.3K +91 +0.9%
Lazard Asset Management
288
Lazard Asset Management
New York
$4.04M +$177K +401 +4%
OSAM
289
O'Shaughnessy Asset Management
Connecticut
$3.95M +$274K +619 +7%
AC
290
Allstate Corporation
Illinois
$3.91M +$2.33M +5,258 +115%
ERSOT
291
Employees Retirement System of Texas
Texas
$3.89M
William Blair & Company
292
William Blair & Company
Illinois
$3.89M -$208K -470 -5%
Commonwealth Equity Services
293
Commonwealth Equity Services
Massachusetts
$3.87M +$150K +338 +4%
Nisa Investment Advisors
294
Nisa Investment Advisors
Missouri
$3.84M -$1.1M -2,484 -20%
Pacer Advisors
295
Pacer Advisors
Pennsylvania
$3.81M +$4.24M +9,588 New
CCIA
296
Campbell & Co Investment Adviser
Maryland
$3.77M -$1.42M -3,207 -25%
JSSH
297
J. Safra Sarasin Holding
$3.63M -$170K -384 -4%
MAM
298
Martingale Asset Management
Massachusetts
$3.63M +$4.04M +9,124 New
Capstone Investment Advisors
299
Capstone Investment Advisors
New York
$3.55M +$3.4M +7,687 +624%
KI
300
Keystone Investors
Singapore
$3.53M +$3.93M +8,880 New