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Alnylam Pharmaceuticals

846 hedge funds and large institutions have $51.7B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 169 funds opening new positions, 288 increasing their positions, 290 reducing their positions, and 118 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

0.83% less ownership

Funds ownership: 99.03%98.2% (-0.83%)

13% less capital invested

Capital invested by funds: $59.2B → $51.7B (-$7.48B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
846
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$494M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$149M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M
5
Morgan Stanley
Morgan Stanley
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
URS
226
Utah Retirement Systems
Utah
$8.24M
Thrivent Financial for Lutherans
227
Thrivent Financial for Lutherans
Minnesota
$8.21M
FISPB
228
Fideuram - Intesa Sanpaolo Private Banking
$8.14M
Stifel Financial
229
Stifel Financial
Missouri
$8.12M
EGM
230
Engineers Gate Manager
New York
$8.03M
AG
231
AIA Group
Hong Kong
$8.02M
Teacher Retirement System of Texas
232
Teacher Retirement System of Texas
Texas
$7.97M
EF
233
Empowered Funds
Pennsylvania
$7.73M
PFSRSONJ
234
Police & Firemen's Retirement System of New Jersey
New Jersey
$7.67M
LIP
235
Liontrust Investment Partners
United Kingdom
$7.31M
Wealthfront Advisers
236
Wealthfront Advisers
California
$7.26M
SCM
237
Silvant Capital Management
Georgia
$7.14M
VIM
238
Vinva Investment Management
Australia
$7.14M
IGAM
239
iA Global Asset Management
Quebec, Canada
$7.07M
MML Investors Services
240
MML Investors Services
Massachusetts
$7.02M
Cetera Investment Advisers
241
Cetera Investment Advisers
Illinois
$6.98M
EMPI
242
Elo Mutual Pension Insurance
Finland
$6.94M
AGP
243
Artia Global Partners
Florida
$6.92M
PM
244
Prosight Management
Texas
$6.8M
ET
245
Entropy Technologies
New York
$6.4M
AssetMark Inc
246
AssetMark Inc
California
$6.38M
SMDAM
247
Sumitomo Mitsui DS Asset Management
Japan
$6.31M
OAM
248
Oppenheimer Asset Management
New York
$6.2M
PA
249
Profund Advisors
Maryland
$6.2M
MOACM
250
Mutual of America Capital Management
New York
$6.15M