|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$616M
|
+$21.8M
|
+243,889
|
+5%
|
|
|
2
|
Capital World Investors
Los Angeles,
California
|
$347M
|
+$176M
|
+1,966,877
|
+174%
|
|
|
3
|
Third Rock Ventures
Boston,
Massachusetts
|
$344M
|
–
|
–
|
–
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$226M
|
+$31.4M
|
+351,290
|
+21%
|
|
|
5
|
Flagship Ventures 2007 General Partner
Cambridge,
Massachusetts
|
$216M
|
–
|
–
|
–
|
|
|
6
|
BB Biotech
Schaffhausen,
Switzerland
|
$209M
|
-$2.29M
|
-25,600
|
-1%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$145M
|
+$18.9M
|
+212,194
|
+20%
|
|
|
8
|
Capital International Investors
Los Angeles,
California
|
$96M
|
+$76.5M
|
+856,400
|
New
|
|
|
9
|
BlackRock Fund Advisors
San Francisco,
California
|
$88M
|
+$6.3M
|
+70,604
|
+10%
|
|
|
10
|
Capital Guardian Trust
Los Angeles,
California
|
$75.6M
|
+$60.3M
|
+674,890
|
New
|
|
|
11
|
BlackRock Advisors
Wilmington,
Delaware
|
$42.9M
|
+$8.22M
|
+92,057
|
+32%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$41.8M
|
-$15.2M
|
-170,801
|
-31%
|
|
|
13
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$33.8M
|
-$84.8M
|
-950,278
|
-76%
|
|
|
14
|
BlackRock Institutional Trust
San Francisco,
California
|
$32.2M
|
+$13.1M
|
+146,666
|
+104%
|
|
|
15
|
ClearBridge Investments
New York
|
$30.9M
|
+$83K
|
+930
|
+0.3%
|
|
|
16
|
Eventide Asset Management
Boston,
Massachusetts
|
$28.9M
|
-$15.5M
|
-173,400
|
-40%
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$28.3M
|
+$20.4M
|
+229,014
|
+987%
|
|
|
18
|
|
$25.9M
|
+$1.87M
|
+20,927
|
+10%
|
|
|
19
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$21.5M
|
+$3.37M
|
+37,700
|
+24%
|
|
|
20
|
|
$21.3M
|
+$4.18M
|
+46,850
|
+33%
|
|
|
21
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$19.6M
|
+$6.67M
|
+74,687
|
+75%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$18.5M
|
+$1.7M
|
+19,036
|
+13%
|
|
|
23
|
|
$18.4M
|
+$2.38M
|
+26,700
|
+19%
|
|
|
24
|
Baker Bros. Advisors
New York
|
$18.3M
|
-$580K
|
-6,500
|
-4%
|
|
|
25
|
Jennison Associates
New York
|
$17.5M
|
-$7.25M
|
-81,148
|
-34%
|
|
