|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$263M
|
+$4.6M
|
+87,744
|
+1%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$245M
|
+$4.39M
|
+83,737
|
+1%
|
|
|
3
|
BB Biotech
Schaffhausen,
Switzerland
|
$117M
|
+$8.4M
|
+160,000
|
+6%
|
|
|
4
|
Capital International Investors
Los Angeles,
California
|
$117M
|
+$67.8M
|
+1,291,390
|
+86%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$103M
|
+$5.46M
|
+104,011
|
+4%
|
|
|
6
|
ClearBridge Investments
New York
|
$64.2M
|
+$4.2M
|
+80,088
|
+5%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$53.9M
|
+$2.77M
|
+52,812
|
+4%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$51.8M
|
+$7.88M
|
+150,244
|
+14%
|
|
|
9
|
Flagship Pioneering
Cambridge,
Massachusetts
|
$40.3M
|
–
|
–
|
–
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$38.3M
|
+$5.61M
|
+106,902
|
+13%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$36.3M
|
+$9.06M
|
+172,662
|
+25%
|
|
|
12
|
Capital Guardian Trust
Los Angeles,
California
|
$34.1M
|
+$9.24M
|
+176,000
|
+27%
|
|
|
13
|
|
$31.3M
|
+$18.4M
|
+350,000
|
+88%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$30.8M
|
+$28.9K
|
+551
|
+0.1%
|
|
|
15
|
Balyasny Asset Management
Chicago,
Illinois
|
$28.6M
|
-$12.4M
|
-235,622
|
-26%
|
|
|
16
|
Capital World Investors
Los Angeles,
California
|
$27.7M
|
–
|
–
|
–
|
|
|
17
|
Columbia Wanger Asset Management
Chicago,
Illinois
|
$26.6M
|
+$560K
|
+10,663
|
+2%
|
|
|
18
|
First Trust Advisors
Wheaton,
Illinois
|
$22.7M
|
-$5.64M
|
-107,465
|
-17%
|
|
|
19
|
Janus Henderson Investors US
Denver,
Colorado
|
$16M
|
+$2.39M
|
+45,509
|
+13%
|
|
|
20
|
Capital International
Los Angeles,
California
|
$14.4M
|
+$4.27M
|
+81,337
|
+31%
|
|
|
21
|
Eventide Asset Management
Boston,
Massachusetts
|
$12.6M
|
–
|
–
|
–
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$10.2M
|
+$1.26M
|
+24,061
|
+11%
|
|
|
23
|
Millennium Management
New York
|
$10.1M
|
+$8.14M
|
+155,070
|
+178%
|
|
|
24
|
|
$10M
|
-$2.2M
|
-41,943
|
-15%
|
|
|
25
|
Columbus Circle Investors
|
$9.71M
|
-$3.69M
|
-70,254
|
-23%
|
|
