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AC Immune
ACIU

41 hedge funds and large institutions have $48.5M invested in AC Immune in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more call options, than puts

Call options by funds: $89K | Put options by funds: $43K

7% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 14

1.26% less ownership

Funds ownership: 27.46% → 26.2% (-1.3%)

9% less funds holding

Funds holding: 45 → 41 (-4)

34% less capital invested

Capital invested by funds: $73.9M → $48.5M (-$25.4M)

44% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 9

Holders
41
Holders Change
-4
Holders Change %
-8.89%
% of All Funds
0.55%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
5
Increased
15
Reduced
14
Closed
9
Calls
$89K
Puts
$43K
Net Calls
+$46K
Net Calls Change
-$91K

Top Buyers

Rank Fund Capital Flow
1
BI
BVF Inc
California
+$756K
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$435K
3
Marshall Wace
Marshall Wace
United Kingdom
+$367K
4
Citadel Advisors
Citadel Advisors
Florida
+$362K
5
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$267K

Top Sellers

Rank Fund Capital Flow
1
RG
Redmile Group
California
-$2.79M
2
BlackRock
BlackRock
New York
-$2.66M
3
PIM
Platinum Investment Management
Australia
-$536K
4
Morgan Stanley
Morgan Stanley
New York
-$238K
5
Two Sigma Investments
Two Sigma Investments
New York
-$110K
Name Holding Trade Value Shares
Change 		Change in
Stake
BI
1
BVF Inc
California
$37.1M +$756K +300,000 +2%
BlackRock
2
BlackRock
New York
$2.16M -$2.66M -1,055,931 -48%
Wells Fargo
3
Wells Fargo
California
$1.87M +$5K +1,985 +0.2%
Renaissance Technologies
4
Renaissance Technologies
New York
$1.5M +$159K +63,271 +9%
PIM
5
Platinum Investment Management
Australia
$1.38M -$536K -212,727 -22%
Northern Trust
6
Northern Trust
Illinois
$705K -$65.4K -25,945 -6%
Acadian Asset Management
7
Acadian Asset Management
Massachusetts
$679K +$435K +172,796 +87%
Deutsche Bank
8
Deutsche Bank
Germany
$474K – – –
Dimensional Fund Advisors
9
Dimensional Fund Advisors
Texas
$445K +$267K +106,148 +81%
Millennium Management
10
Millennium Management
New York
$398K +$236K +93,710 +79%
Marshall Wace
11
Marshall Wace
United Kingdom
$397K +$367K +145,866 +220%
Citadel Advisors
12
Citadel Advisors
Florida
$283K +$362K +143,598 +1,826%
Handelsbanken Fonder
13
Handelsbanken Fonder
Sweden
$243K -$50.4K -20,000 -13%
EP
14
Eversept Partners
New York
$188K +$254K +100,752 New
Morgan Stanley
15
Morgan Stanley
New York
$135K -$238K -94,551 -57%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$120K – – –
BCV
17
Banque Cantonale Vaudoise
Switzerland
$50K +$67.3K +26,712 New
SEI Investments
18
SEI Investments
Pennsylvania
$46.6K +$62.7K +24,897 New
Two Sigma Advisers
19
Two Sigma Advisers
New York
$44.2K +$25.7K +10,200 +76%
Squarepoint
20
Squarepoint
New York
$41.9K -$53.9K -21,378 -49%
CF
21
Cantor Fitzgerald
New York
$37.4K -$12.6K -5,000 -20%
CUAMC
22
China Universal Asset Management Company
China
$37.1K -$2.85K -1,133 -5%
UBS Group
23
UBS Group
Switzerland
$31.2K -$83.1K -32,990 -66%
QOP
24
Quinn Opportunity Partners
Virginia
$18.9K – – –
SBCM
25
Silverberg Bernstein Capital Management
New York
$18.7K – – –
1
2

ACIU Hedge Fund Activity: Q1 2025 in Review

41 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AC Immune (ACIU) for Q1 2025, worth a combined $48.5M — down 34% from $73.9M a quarter earlier.

Sellers outnumbered buyers: 9 funds closed out of ACIU and 5 opened new positions — a net loss of 4 holders — while 14 trimmed existing stakes and 15 added.

The largest buyer was BVF Inc, adding an estimated $756K. The largest seller was Redmile Group, exiting entirely with an estimated $2.79M sold.

  • 41 institutional investors held AC Immune (ACIU) as of Q1 2025, down from 45 in Q4 2024.
  • Funds reported $48.5M of AC Immune stock for Q1 2025, down 34% quarter-over-quarter.
  • 5 funds opened new AC Immune positions in Q1 2025 and 9 closed out, a net change of -4 holders.
  • The largest AC Immune buyer in Q1 2025 was BVF Inc, an estimated $756K added.
  • The largest AC Immune seller in Q1 2025 was Redmile Group, an estimated $2.79M sold.

Based on aggregated 13F filings for Q1 2025.