Two Sigma Investments’s AC Immune ACIU Stock Holding History

Two Sigma Investments’s Portfolio ACIU Stock Details ACIU Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$245K	Buy	102,825 +63,734	+163%	+$176K	﹤0.01%	4648
2026 Q1	$108K	Sell	39,091 -48,793	-56%	-$152K	﹤0.01%	4380
2025 Q4	$276K	Buy	87,884 +71,109	+424%	+$224K	﹤0.01%	3616
2025 Q3	$48.5K	Sell	16,775 -13,915	-45%	-$31.4K	﹤0.01%	3544
2025 Q2	$62.3K	Buy	+30,690	New	+$53.4K	﹤0.01%	3050
2025 Q1	–	Sell	-40,818	Closed	-$110K	–	3164
2024 Q4	$110K	Sell	40,818 -16,503	-29%	-$51.6K	﹤0.01%	2959
2024 Q3	$217K	Sell	57,321 -42,022	-42%	-$147K	﹤0.01%	2785
2024 Q2	$396K	Buy	+99,343	New	+$329K	﹤0.01%	2472
2023 Q3	–	Sell	-15,279	Closed	-$45.1K	–	2931
2023 Q2	$45.1K	Buy	+15,279	New	+$33.3K	﹤0.01%	2842
2021 Q4	–	Sell	-64,051	Closed	-$430K	–	4195
2021 Q3	$430K	Sell	64,051 -134,243	-68%	-$961K	﹤0.01%	3384
2021 Q2	$1.57M	Buy	+198,294	New	+$1.37M	﹤0.01%	2090

Other funds holding ACIU

Wells Fargo San Francisco, California $617B AUM 30.33% 1-Year Est. Return

Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return

Arrowstreet Capital Boston, Massachusetts $225B AUM 49.49% 1-Year Est. Return

Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

Qube Research & Technologies (QRT) London, United Kingdom $108B AUM 37.29% 1-Year Est. Return

UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

Two Sigma Investments's ACIU Position: Q2 2026 in Review

Two Sigma Investments increased its AC Immune (ACIU) stake by 163% in Q2 2026, buying an estimated $176K and bringing the position to 102,825 shares worth $245K. The position accounts for ﹤0.01% of the portfolio, ranked #4648.

Two Sigma Investments first reported a position in ACIU in Q2 2021 and has held it in 11 quarters since. The position peaked at $1.57M in Q2 2021. 40 funds tracked by Wall St. Rank hold ACIU as of Q2 2026.

Two Sigma Investments held 102,825 shares of AC Immune worth $245K as of Q2 2026.
Two Sigma Investments bought 63,734 AC Immune shares in Q2 2026, an estimated $176K.
AC Immune made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #4648 holding.
Two Sigma Investments first reported a position in AC Immune in Q2 2021 and has held it in 11 quarters since.
Two Sigma Investments's AC Immune position peaked at $1.57M in Q2 2021.
40 funds tracked by Wall St. Rank held AC Immune as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.