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AC Immune

40 hedge funds and large institutions have $71.1M invested in AC Immune in 2025 Q3 according to their latest regulatory filings, with 4 funds opening new positions, 14 increasing their positions, 12 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

237% more call options, than puts

Call options by funds: $293K | Put options by funds: $87K

43% more capital invested

Capital invested by funds: $49.7M → $71.1M (+$21.4M)

17% more repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 12

0.12% more ownership

Funds ownership: 24.4%24.52% (+0.12%)

5% less funds holding

Funds holding: 4240 (-2)

33% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 6

Holders
40
Holders Change
-2
Holders Change %
-4.76%
% of All Funds
0.52%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
4
Increased
14
Reduced
12
Closed
6
Calls
$293K
Puts
$87K
Net Calls
+$206K
Net Calls Change
+$298K
Name Holding Trade Value Shares
Change
Change in
Stake
BI
1
BVF Inc
California
$57.3M
Wells Fargo
2
Wells Fargo
California
$2.92M -$31.8K -14,087 -1%
Millennium Management
3
Millennium Management
New York
$2.59M +$1.36M +603,000 +207%
Renaissance Technologies
4
Renaissance Technologies
New York
$2.23M -$131K -57,902 -7%
BlackRock
5
BlackRock
New York
$1.19M +$1.22K +541 +0.1%
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$1.18M +$3.48K +1,541 +0.4%
Northern Trust
7
Northern Trust
Illinois
$815K -$224K -99,401 -26%
Deutsche Bank
8
Deutsche Bank
Germany
$732K
Assenagon Asset Management
9
Assenagon Asset Management
Luxembourg
$549K +$429K +189,892 New
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$513K -$48.7K -21,575 -11%
Morgan Stanley
11
Morgan Stanley
New York
$266K +$43.2K +19,138 +26%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$184K
Susquehanna International Group
13
Susquehanna International Group
Pennsylvania
$63.1K +$49.3K +21,840 New
Two Sigma Advisers
14
Two Sigma Advisers
New York
$60.5K -$17.8K -7,872 -27%
Citadel Advisors
15
Citadel Advisors
Florida
$58.1K -$284K -125,886 -86%
BCV
16
Banque Cantonale Vaudoise
Switzerland
$53K
CUAMC
17
China Universal Asset Management Company
China
$50.9K -$5.8K -2,567 -13%
Two Sigma Investments
18
Two Sigma Investments
New York
$48.5K -$31.4K -13,915 -45%
PAG
19
Private Advisor Group
New Jersey
$48K +$37.5K +16,600 New
UBS Group
20
UBS Group
Switzerland
$47.5K +$20.2K +8,957 +120%
SEI Investments
21
SEI Investments
Pennsylvania
$45.9K -$20.4K -9,013 -36%
Goldman Sachs
22
Goldman Sachs
New York
$36.5K +$5.12K +2,266 +22%
QOP
23
Quinn Opportunity Partners
Virginia
$29.2K
SBCM
24
Silverberg Bernstein Capital Management
New York
$28.9K
JP Morgan Chase
25
JP Morgan Chase
New York
$21K +$2.6K +1,149 +19%

ACIU Hedge Fund Activity: Q3 2025 in Review

40 of the 7,631 institutional investors tracked by Wall St. Rank reported a position in AC Immune (ACIU) for Q3 2025, worth a combined $71.1M — up 43% from $49.7M a quarter earlier.

Sellers outnumbered buyers: 6 funds closed out of ACIU and 4 opened new positions — a net loss of 2 holders — while 12 trimmed existing stakes and 14 added.

The largest buyer was Millennium Management, adding an estimated $1.36M. The largest seller was Citadel Advisors, cutting an estimated $284K.

  • 40 institutional investors held AC Immune (ACIU) as of Q3 2025, down from 42 in Q2 2025.
  • Funds reported $71.1M of AC Immune stock for Q3 2025, up 43% quarter-over-quarter.
  • 4 funds opened new AC Immune positions in Q3 2025 and 6 closed out, a net change of -2 holders.
  • The largest AC Immune buyer in Q3 2025 was Millennium Management, an estimated $1.36M added.
  • The largest AC Immune seller in Q3 2025 was Citadel Advisors, an estimated $284K sold.

Based on aggregated 13F filings for Q3 2025.