AC Immune
ACIU
41 hedge funds and large institutions have $80.9M invested in AC Immune in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 15 increasing their positions, 10 reducing their positions, and 6 closing their positions.
841% more call options, than puts
Call options by funds: $1.12M | Put options by funds: $119K
50% more repeat investments, than reductions
Existing positions increased: 15 | Existing positions reduced: 10
17% more first-time investments, than exits
New positions opened: 7 | Existing positions closed: 6
14% more capital invested
Capital invested by funds: $71.1M → $80.9M (+$9.77M)
3% more funds holding
Funds holding: 40 → 41 (+1)
1.15% more ownership
Funds ownership: 24.52% → 25.67% (+1.1%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Point72 Asset Management
Stamford,
Connecticut
|
+$1.21M |
| 2 |
Arrowstreet Capital
Boston,
Massachusetts
|
+$1.18M |
| 3 |
Marshall Wace
London,
United Kingdom
|
+$589K |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$561K |
| 5 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
+$397K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
-$732K |
| 2 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
-$549K |
| 3 |
Renaissance Technologies
New York
|
-$320K |
| 4 |
Two Sigma Advisers
New York
|
-$60.5K |
| 5 |
PAG
Private Advisor Group
Morristown,
New Jersey
|
-$48K |
ACIU Hedge Fund Activity: Q4 2025 in Review
41 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in AC Immune (ACIU) for Q4 2025, worth a combined $80.9M — up 14% from $71.1M a quarter earlier.
Buyers outnumbered sellers: 7 funds opened new ACIU positions and 6 closed out — a net gain of 1 holder — while 15 added to existing stakes and 10 trimmed.
The largest buyer was Point72 Asset Management, opening a new position worth an estimated $1.21M. The largest seller was Deutsche Bank, exiting entirely with an estimated $732K sold.
- 41 institutional investors held AC Immune (ACIU) as of Q4 2025, up from 40 in Q3 2025.
- Funds reported $80.9M of AC Immune stock for Q4 2025, up 14% quarter-over-quarter.
- 7 funds opened new AC Immune positions in Q4 2025 and 6 closed out, a net change of +1 holder.
- The largest AC Immune buyer in Q4 2025 was Point72 Asset Management, an estimated $1.21M added.
- The largest AC Immune seller in Q4 2025 was Deutsche Bank, an estimated $732K sold.
Based on aggregated 13F filings for Q4 2025.