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AC Immune
ACIU

41 hedge funds and large institutions have $48.5M invested in AC Immune in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more call options, than puts

Call options by funds: $89K | Put options by funds: $43K

7% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 14

1.26% less ownership

Funds ownership: 27.46% → 26.2% (-1.3%)

9% less funds holding

Funds holding: 45 → 41 (-4)

34% less capital invested

Capital invested by funds: $73.9M → $48.5M (-$25.4M)

44% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 9

Holders
41
Holders Change
-4
Holders Change %
-8.89%
% of All Funds
0.55%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
5
Increased
15
Reduced
14
Closed
9
Calls
$89K
Puts
$43K
Net Calls
+$46K
Net Calls Change
-$91K

Top Buyers

Rank Fund Capital Flow
1
BI
BVF Inc
California
+$756K
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$435K
3
Marshall Wace
Marshall Wace
United Kingdom
+$367K
4
Citadel Advisors
Citadel Advisors
Florida
+$362K
5
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$267K

Top Sellers

Rank Fund Capital Flow
1
RG
Redmile Group
California
-$2.79M
2
BlackRock
BlackRock
New York
-$2.66M
3
PIM
Platinum Investment Management
Australia
-$536K
4
Morgan Stanley
Morgan Stanley
New York
-$238K
5
Two Sigma Investments
Two Sigma Investments
New York
-$110K
Name Holding Trade Value Shares
Change 		Change in
Stake
Barclays
26
Barclays
United Kingdom
$13.9K +$3.87K +1,537 +26%
JP Morgan Chase
27
JP Morgan Chase
New York
$13.3K -$3.32K -1,317 -16%
TRCT
28
Tower Research Capital (TRC)
New York
$12.8K -$123 -49 -0.7%
State of Tennessee, Department of Treasury
29
State of Tennessee, Department of Treasury
Tennessee
$9.59K +$12.9K +5,126 New
Mirae Asset Global Investments
30
Mirae Asset Global Investments
South Korea
$6.55K +$33 +13 +0.4%
Bank of America
31
Bank of America
North Carolina
$4.7K -$950 -377 -13%
GFM
32
GF Fund Management
China
$4.59K +$950 +377 +18%
Royal Bank of Canada
33
Royal Bank of Canada
Ontario, Canada
$3K +$1.7K +675 +69%
Citigroup
34
Citigroup
New York
$2.69K -$3.25K -1,288 -47%
BNP Paribas Financial Markets
35
BNP Paribas Financial Markets
France
$2.27K -$2K -792 -40%
AWM
36
Activest Wealth Management
Florida
$1.87K – – –
SS
37
SBI Securities
Japan
$1.05K +$43 +17 +3%
Lazard Asset Management
38
Lazard Asset Management
New York
$1K +$141 +56 +7%
SIC
39
SJS Investment Consulting
Ohio
$374 – – –
SFCL
40
Strengthening Families & Communities LLC
Massachusetts
$374 – – –
RG
41
Redmile Group
California
– -$2.79M -1,034,299 Closed
Two Sigma Investments
42
Two Sigma Investments
New York
– -$110K -40,818 Closed
Jane Street
43
Jane Street
New York
– -$65.6K -24,283 Closed
RL
44
RPO LLC
Connecticut
– -$50.6K -18,728 Closed
SOW
45
State of Wyoming
Wyoming
– -$49.2K -18,219 Closed
BFM
46
Boothbay Fund Management
New York
– -$37.9K -14,046 Closed
CSS
47
Cubist Systematic Strategies
Connecticut
– -$31.5K -11,667 Closed
CLOS
48
Compagnie Lombard Odier SCmA
Switzerland
– -$25.2K -10,000 Closed
Zurich Cantonal Bank
49
Zurich Cantonal Bank
Switzerland
– -$8.43K -3,123 Closed
Simplex Trading
50
Simplex Trading
Illinois
– +$715 +284 New
1
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ACIU Hedge Fund Activity: Q1 2025 in Review

41 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AC Immune (ACIU) for Q1 2025, worth a combined $48.5M — down 34% from $73.9M a quarter earlier.

Sellers outnumbered buyers: 9 funds closed out of ACIU and 5 opened new positions — a net loss of 4 holders — while 14 trimmed existing stakes and 15 added.

The largest buyer was BVF Inc, adding an estimated $756K. The largest seller was Redmile Group, exiting entirely with an estimated $2.79M sold.

  • 41 institutional investors held AC Immune (ACIU) as of Q1 2025, down from 45 in Q4 2024.
  • Funds reported $48.5M of AC Immune stock for Q1 2025, down 34% quarter-over-quarter.
  • 5 funds opened new AC Immune positions in Q1 2025 and 9 closed out, a net change of -4 holders.
  • The largest AC Immune buyer in Q1 2025 was BVF Inc, an estimated $756K added.
  • The largest AC Immune seller in Q1 2025 was Redmile Group, an estimated $2.79M sold.

Based on aggregated 13F filings for Q1 2025.