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Upstream Bio Inc
UPB

Nome Posição Valor negociado Ações
Variação 		Variação na
participação
Fidelity Investments
1
Fidelity Investments
Massachusetts
US$ 56,5 mi +US$ 514 mil +61.334 +0,8%
OrbiMed
2
OrbiMed
New York
US$ 39,4 mi – – –
Norges Bank
3
Norges Bank
Norway
US$ 26,1 mi +US$ 31,6 mi +3.768.619 Nova
BlackRock
4
BlackRock
New York
US$ 26 mi +US$ 3,21 mi +382.669 +11%
Decheng Capital
5
Decheng Capital
California
US$ 18,9 mi – – –
ES
6
Enavate Sciences
California
US$ 17 mi – – –
Vanguard Capital Management
7
Vanguard Capital Management
Pennsylvania
US$ 13 mi +US$ 26,5 mil +3.160 +0,2%
Millennium Management
8
Millennium Management
New York
US$ 7,91 mi +US$ 1,73 mi +206.452 +22%
D.E. Shaw & Co
9
D.E. Shaw & Co
New York
US$ 7,17 mi +US$ 1,81 mi +215.564 +26%
JP Morgan Chase
10
JP Morgan Chase
New York
US$ 7,01 mi +US$ 4,6 mi +549.043 +119%
Qube Research & Technologies (QRT)
11
Qube Research & Technologies (QRT)
United Kingdom
US$ 6,77 mi +US$ 3,01 mi +359.179 +58%
Parkman Healthcare Partners
12
Parkman Healthcare Partners
Connecticut
US$ 6,47 mi +US$ 1,24 mi +148.464 +19%
Geode Capital Management
13
Geode Capital Management
Massachusetts
US$ 6,45 mi -US$ 162 mil -19.356 -2%
SEB Asset Management
14
SEB Asset Management
US$ 6,08 mi – – –
Woodline Partners
15
Woodline Partners
California
US$ 5,75 mi – – –
State Street
16
State Street
Massachusetts
US$ 5,3 mi +US$ 511 mil +60.973 +9%
Vanguard Portfolio Management
17
Vanguard Portfolio Management
Pennsylvania
US$ 4,93 mi -US$ 126 mil -15.044 -2%
Y-Intercept (HK)
18
Y-Intercept (HK)
Hong Kong
US$ 4,8 mi -US$ 2,57 mi -307.076 -31%
Bain Capital Life Sciences Investors
19
Bain Capital Life Sciences Investors
Massachusetts
US$ 4,16 mi -US$ 2,23 mi -266.262 -31%
AQR Capital Management
20
AQR Capital Management
Connecticut
US$ 3,77 mi +US$ 3,96 mi +472.698 +655%
Morgan Stanley
21
Morgan Stanley
New York
US$ 3,63 mi -US$ 234 mil -27.977 -5%
BNP Paribas Financial Markets
22
BNP Paribas Financial Markets
France
US$ 3,54 mi +US$ 3,23 mi +385.546 +306%
Walleye Capital
23
Walleye Capital
New York
US$ 3,45 mi +US$ 4,18 mi +498.490 Nova
Trexquant Investment
24
Trexquant Investment
Connecticut
US$ 3,23 mi +US$ 2,43 mi +289.773 +164%
Point72 Asset Management
25
Point72 Asset Management
Connecticut
US$ 3,13 mi +US$ 2,3 mi +274.843 +154%
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