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PBYI

Nome Posição Valor negociado Ações
Variação 		Variação na
participação
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
US$ 1,08 bi – – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
US$ 764 mi +US$ 276 mi +1.245.921 +45%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
US$ 524 mi -US$ 171 mi -772.722 -22%
Capital Research Global Investors
4
Capital Research Global Investors
California
US$ 368 mi +US$ 24,2 mi +109.240 +6%
Vanguard Group
5
Vanguard Group
Pennsylvania
US$ 288 mi +US$ 4,86 mi +21.899 +1%
BlackRock Fund Advisors
6
BlackRock Fund Advisors
California
US$ 114 mi +US$ 14,8 mi +66.576 +12%
BlackRock Institutional Trust
7
BlackRock Institutional Trust
California
US$ 105 mi +US$ 440 mil +1.981 +0,4%
BB Biotech
8
BB Biotech
Switzerland
US$ 98,8 mi +US$ 10 mi +45.000 +9%
Capital International Investors
9
Capital International Investors
California
US$ 95,3 mi +US$ 112 mi +503.700 Nova
State Street
10
State Street
Massachusetts
US$ 94,1 mi +US$ 8,35 mi +37.622 +8%
Franklin Resources
11
Franklin Resources
California
US$ 89,7 mi -US$ 10,9 mi -49.259 -9%
AllianceBernstein
12
AllianceBernstein
Tennessee
US$ 87,7 mi +US$ 15,7 mi +70.790 +18%
Massachusetts Financial Services
13
Massachusetts Financial Services
Massachusetts
US$ 78,3 mi +US$ 7,96 mi +35.897 +9%
Janus Henderson Investors US
14
Janus Henderson Investors US
Colorado
US$ 72,8 mi +US$ 19,3 mi +87.173 +29%
Wells Fargo
15
Wells Fargo
California
US$ 65,6 mi -US$ 40,9 mi -184.550 -35%
Northern Trust
16
Northern Trust
Illinois
US$ 47,6 mi -US$ 2,13 mi -9.608 -4%
OrbiMed
17
OrbiMed
New York
US$ 47,5 mi +US$ 8,43 mi +38.000 +18%
Orbis Holdings
18
Orbis Holdings
Bermuda
US$ 43,7 mi +US$ 2,97 mi +13.371 +6%
Eagle Asset Management
19
Eagle Asset Management
Florida
US$ 42,6 mi -US$ 577 mil -2.601 -1%
Cormorant Asset Management
20
Cormorant Asset Management
Massachusetts
US$ 41,6 mi -US$ 63,8 mi -287.500 -57%
BlackRock Advisors
21
BlackRock Advisors
Delaware
US$ 39,7 mi -US$ 4,75 mi -21.421 -9%
Fred Alger Management
22
Fred Alger Management
New York
US$ 39,1 mi +US$ 9,9 mi +44.794 +28%
Wellington Management Group
23
Wellington Management Group
Massachusetts
US$ 38,5 mi +US$ 9,48 mi +42.734 +27%
Columbus Circle Investors
24
Columbus Circle Investors
US$ 37,9 mi +US$ 25,6 mi +115.511 +136%
Capital Guardian Trust
25
Capital Guardian Trust
California
US$ 36,2 mi +US$ 42,4 mi +191.000 Nova
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