|
1
|
Tudor Investment Corp
Stamford,
Connecticut
|
US$ 4 mil
|
-US$ 324 mil
|
-218.384
|
Encerrada
|
|
|
2
|
|
–
|
-US$ 46,8 mi
|
-31.841.394
|
Encerrada
|
|
|
3
|
Primecap Management
Pasadena,
California
|
–
|
-US$ 24,5 mi
|
-16.642.727
|
Encerrada
|
|
|
4
|
Newtyn Management
New York
|
–
|
-US$ 11,1 mi
|
-7.569.995
|
Encerrada
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 11,1 mi
|
-7.540.469
|
Encerrada
|
|
|
6
|
Rock Springs Capital Management
Baltimore,
Maryland
|
–
|
-US$ 11 mi
|
-7.485.543
|
Encerrada
|
|
|
7
|
Palo Alto Investors
Palo Alto,
California
|
–
|
-US$ 10 mi
|
-6.774.541
|
Encerrada
|
|
|
8
|
Platinum Investment Management
Sydney Australia 2000,
Australia
|
–
|
-US$ 9,7 mi
|
-6.603.870
|
Encerrada
|
|
|
9
|
Rubric Capital Management (New York)
New York
|
–
|
-US$ 9,24 mi
|
-6.283.690
|
Encerrada
|
|
|
10
|
Woodline Partners
San Francisco,
California
|
–
|
-US$ 5,68 mi
|
-3.866.148
|
Encerrada
|
|
|
11
|
|
–
|
-US$ 5,4 mi
|
-3.673.443
|
Encerrada
|
|
|
12
|
MPM BioImpact
Boston,
Massachusetts
|
–
|
-US$ 5,04 mi
|
-3.425.202
|
Encerrada
|
|
|
13
|
Laurion Capital Management
New York
|
–
|
-US$ 4,24 mi
|
-2.885.100
|
Encerrada
|
|
|
14
|
|
–
|
-US$ 3,87 mi
|
-2.629.998
|
Encerrada
|
|
|
15
|
|
–
|
-US$ 2,54 mi
|
-1.728.102
|
Encerrada
|
|
|
16
|
Millennium Management
New York
|
–
|
-US$ 2,28 mi
|
-1.548.767
|
Encerrada
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-US$ 2,23 mi
|
-1.518.496
|
Encerrada
|
|
|
18
|
Beryl Capital Management
Redondo Beach,
California
|
–
|
-US$ 2,05 mi
|
-1.394.821
|
Encerrada
|
|
|
19
|
Baker Bros. Advisors
New York
|
–
|
-US$ 1,47 mi
|
-1.000.000
|
Encerrada
|
|
|
20
|
GSA Capital Partners
London,
United Kingdom
|
–
|
-US$ 1,37 mi
|
-930.718
|
Encerrada
|
|
|
21
|
Gabelli Funds
Rye,
New York
|
–
|
-US$ 1,25 mi
|
-852.105
|
Encerrada
|
|
|
22
|
|
–
|
-US$ 1,23 mi
|
-836.955
|
Encerrada
|
|
|
23
|
Acadian Asset Management
Boston,
Massachusetts
|
–
|
-US$ 1,18 mi
|
-805.798
|
Encerrada
|
|
|
24
|
Frazier Life Sciences Management
Palo Alto,
California
|
–
|
-US$ 1,09 mi
|
-739.369
|
Encerrada
|
|
|
25
|
State Street
Boston,
Massachusetts
|
–
|
-US$ 1,03 mi
|
-700.331
|
Encerrada
|
|
