|
1
|
Kynam Capital Management
Princeton,
New Jersey
|
–
|
-US$ 25,8 mi
|
-4.420.349
|
Encerrada
|
|
|
2
|
BVF Inc
San Francisco,
California
|
–
|
-US$ 21,2 mi
|
-3.629.000
|
Encerrada
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 11,2 mi
|
-1.910.984
|
Encerrada
|
|
|
4
|
Nantahala Capital Management
New Canaan,
Connecticut
|
–
|
-US$ 10,1 mi
|
-1.732.388
|
Encerrada
|
|
|
5
|
Millennium Management
New York
|
–
|
-US$ 8,42 mi
|
-1.441.735
|
Encerrada
|
|
|
6
|
Citadel Advisors
Miami,
Florida
|
–
|
-US$ 8,13 mi
|
-1.391.302
|
Encerrada
|
|
|
7
|
Point72 Asset Management
Stamford,
Connecticut
|
–
|
-US$ 7,83 mi
|
-1.340.300
|
Encerrada
|
|
|
8
|
Bank of America
Charlotte,
North Carolina
|
–
|
-US$ 7,64 mi
|
-1.308.386
|
Encerrada
|
|
|
9
|
Ingalls & Snyder LLC
New York
|
–
|
-US$ 7,57 mi
|
-1.295.833
|
Encerrada
|
|
|
10
|
|
–
|
-US$ 7,22 mi
|
-1.236.951
|
Encerrada
|
|
|
11
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
–
|
-US$ 7,03 mi
|
-1.203.484
|
Encerrada
|
|
|
12
|
Tang Capital Management
San Diego,
California
|
–
|
-US$ 6,72 mi
|
-1.150.000
|
Encerrada
|
|
|
13
|
RA Capital Management
Boston,
Massachusetts
|
–
|
-US$ 6,36 mi
|
-1.088.296
|
Encerrada
|
|
|
14
|
Sphera Funds Management
Tel Aviv,
Israel
|
–
|
-US$ 5,86 mi
|
-1.002.783
|
Encerrada
|
|
|
15
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
–
|
-US$ 4,49 mi
|
-769.336
|
Encerrada
|
|
|
16
|
Acadian Asset Management
Boston,
Massachusetts
|
–
|
-US$ 4,4 mi
|
-753.140
|
Encerrada
|
|
|
17
|
AWM Investment Company
New York
|
–
|
-US$ 3,89 mi
|
-666.661
|
Encerrada
|
|
|
18
|
|
–
|
-US$ 3,45 mi
|
-591.380
|
Encerrada
|
|
|
19
|
Barclays
London,
United Kingdom
|
–
|
-US$ 3,34 mi
|
-571.990
|
Encerrada
|
|
|
20
|
NewEdge Wealth
Pittsburgh,
Pennsylvania
|
–
|
-US$ 3,2 mi
|
-547.501
|
Encerrada
|
|
|
21
|
Bank of Montreal
Toronto,
Ontario, Canada
|
–
|
-US$ 3,19 mi
|
-543.200
|
Encerrada
|
|
|
22
|
Alyeska Investment Group
Chicago,
Illinois
|
–
|
-US$ 3,15 mi
|
-538.579
|
Encerrada
|
|
|
23
|
|
–
|
-US$ 3,06 mi
|
-523.630
|
Encerrada
|
|
|
24
|
Schonfeld Strategic Advisors
New York
|
–
|
-US$ 2,94 mi
|
-503.674
|
Encerrada
|
|
|
25
|
Renaissance Technologies
New York
|
–
|
-US$ 2,92 mi
|
-500.605
|
Encerrada
|
|
