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XTX Topco’s Puma Biotechnology PBYI Stock Holding History

XTX Topco’s Portfolio PBYI Stock Details PBYI Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$327K Buy
40,296
+25,180
+167% +$184K ﹤0.01% 2837
2026
Q1 		$96.6K Buy
+15,116
New +$97.5K ﹤0.01% 3113
2025
Q4 		– Sell
-25,524
Closed -$136K – 3669
2025
Q3 		$136K Sell
25,524
-78,900
-76% -$335K 0.01% 1955
2025
Q2 		$358K Sell
104,424
-20,893
-17% -$66.7K 0.01% 1316
2025
Q1 		$371K Buy
125,317
+65,643
+110% +$205K 0.02% 1248
2024
Q4 		$182K Buy
59,674
+33,290
+126% +$96.9K 0.02% 1588
2024
Q3 		$67.3K Sell
26,384
-22,227
-46% -$67.3K ﹤0.01% 1656
2024
Q2 		$158K Sell
48,611
-5,542
-10% -$24.3K 0.01% 1316
2024
Q1 		$287K Sell
54,153
-739
-1% -$3.98K 0.04% 897
2023
Q4 		$238K Buy
54,892
+39,603
+259% +$131K 0.05% 821
2023
Q3 		$40.2K Sell
15,289
-63,161
-81% -$215K 0.01% 1302
2023
Q2 		$277K Sell
78,450
-3,169
-4% -$9.89K 0.05% 774
2023
Q1 		$252K Sell
81,619
-12,736
-13% -$48K 0.05% 789
2022
Q4 		$399K Buy
94,355
+66,299
+236% +$229K 0.08% 412
2022
Q3 		$66K Sell
28,056
-8,074
-22% -$23.6K 0.02% 997
2022
Q2 		$103K Sell
36,130
-25,088
-41% -$62.4K 0.04% 638
2022
Q1 		$176K Buy
61,218
+30,910
+102% +$80K 0.08% 438
2021
Q4 		$92K Buy
+30,308
New +$132K 0.05% 478
2021
Q3 		– Sell
-15,705
Closed -$144K – 971
2021
Q2 		$144K Buy
+15,705
New +$159K 0.05% 611

Other funds holding PBYI

ACA
Acorn Capital Advisors New York $366M AUM 474.6% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $84.2B AUM 55.88% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
LSV Asset Management
LSV Asset Management Chicago, Illinois $55.1B AUM 45.38% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $552B AUM 44.19% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

XTX Topco's PBYI Position: Q2 2026 in Review

XTX Topco increased its Puma Biotechnology (PBYI) stake by 167% in Q2 2026, buying an estimated $184K and bringing the position to 40,296 shares worth $327K. The position accounts for ﹤0.01% of the portfolio, ranked #2837.

XTX Topco first reported a position in PBYI in Q2 2021 and has held it in 19 quarters since. The position peaked at $399K in Q4 2022. 160 funds tracked by Wall St. Rank hold PBYI as of Q2 2026.

  • XTX Topco held 40,296 shares of Puma Biotechnology worth $327K as of Q2 2026.
  • XTX Topco bought 25,180 Puma Biotechnology shares in Q2 2026, an estimated $184K.
  • Puma Biotechnology made up ﹤0.01% of XTX Topco's portfolio in Q2 2026, its #2837 holding.
  • XTX Topco first reported a position in Puma Biotechnology in Q2 2021 and has held it in 19 quarters since.
  • XTX Topco's Puma Biotechnology position peaked at $399K in Q4 2022.
  • 160 funds tracked by Wall St. Rank held Puma Biotechnology as of Q2 2026.

Based on XTX Topco's 13F filing for Q2 2026, filed 14 Aug 2026.