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Virginia Retirement Systems’s Spyre Therapeutics SYRE Stock Holding History

Virginia Retirement Systems’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$817K Buy
24,950
+6,450
+35% +$169K ﹤0.01% 646
2025
Q3 		$310K Buy
+18,500
New +$302K ﹤0.01% 839

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
FFM
Fairmount Funds Management West Conshohocken, Pennsylvania $1.38B AUM 407.79% 1-Year Est. Return
VA
VR Adviser New York $2.68B AUM 422.73% 1-Year Est. Return
Capital International Investors
Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return

Virginia Retirement Systems's SYRE Position: Q4 2025 in Review

Virginia Retirement Systems increased its Spyre Therapeutics (SYRE) stake by 35% in Q4 2025, buying an estimated $169K and bringing the position to 24,950 shares worth $817K. The position accounts for ﹤0.01% of the portfolio, ranked #646.

Virginia Retirement Systems first reported a position in SYRE in Q3 2025 and has held it in 2 quarters since. 153 funds tracked by Wall St. Rank hold SYRE as of Q4 2025.

  • Virginia Retirement Systems held 24,950 shares of Spyre Therapeutics worth $817K as of Q4 2025.
  • Virginia Retirement Systems bought 6,450 Spyre Therapeutics shares in Q4 2025, an estimated $169K.
  • Spyre Therapeutics made up ﹤0.01% of Virginia Retirement Systems's portfolio in Q4 2025, its #646 holding.
  • Virginia Retirement Systems first reported a position in Spyre Therapeutics in Q3 2025 and has held it in 2 quarters since.
  • 153 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q4 2025.

Based on Virginia Retirement Systems's 13F filing for Q4 2025, filed 4 Feb 2026.