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Virginia Retirement Systems’s Spyre Therapeutics SYRE Stock Holding History

Virginia Retirement Systems’s Portfolio SYRE Stock Details SYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$999K Sell
11,250
-16,300
-59% -$1.19M 0.01% 757
2026
Q1 		$1.39M Buy
27,550
+2,600
+10% +$98K 0.01% 503
2025
Q4 		$817K Buy
24,950
+6,450
+35% +$169K ﹤0.01% 646
2025
Q3 		$310K Buy
+18,500
New +$302K ﹤0.01% 839

Other funds holding SYRE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $5.34B AUM 380.18% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
VA
VR Adviser New York $3.3B AUM 525.74% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

Virginia Retirement Systems's SYRE Position: Q2 2026 in Review

Virginia Retirement Systems reduced its Spyre Therapeutics (SYRE) stake by 59% in Q2 2026, selling an estimated $1.19M and leaving 11,250 shares worth $999K. The position accounts for 0.01% of the portfolio, ranked #757.

Virginia Retirement Systems first reported a position in SYRE in Q3 2025 and has held it in 4 quarters since. The position peaked at $1.39M in Q1 2026. 266 funds tracked by Wall St. Rank hold SYRE as of Q2 2026.

  • Virginia Retirement Systems held 11,250 shares of Spyre Therapeutics worth $999K as of Q2 2026.
  • Virginia Retirement Systems sold 16,300 Spyre Therapeutics shares in Q2 2026, an estimated $1.19M.
  • Spyre Therapeutics made up 0.01% of Virginia Retirement Systems's portfolio in Q2 2026, its #757 holding.
  • Virginia Retirement Systems first reported a position in Spyre Therapeutics in Q3 2025 and has held it in 4 quarters since.
  • Virginia Retirement Systems's Spyre Therapeutics position peaked at $1.39M in Q1 2026.
  • 266 funds tracked by Wall St. Rank held Spyre Therapeutics as of Q2 2026.

Based on Virginia Retirement Systems's 13F filing for Q2 2026, filed 25 Aug 2026.