Two Sigma Securities’s Zymeworks ZYME Stock Holding History

Two Sigma Securities’s Portfolio ZYME Stock Details ZYME Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-12,225	Closed	-$209K	–	2104
2025 Q3	$209K	Buy	+12,225	New	+$175K	0.03%	790

Other funds holding ZYME

EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return

RCMNY

Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return

BNP Paribas Asset Management Paris, France $86.1B AUM 29.11% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return

Deutsche Bank Frankfurt Am Main Ge, Germany $303B AUM 30.15% 1-Year Est. Return

Two Sigma Securities's ZYME Position: Q4 2025 in Review

Two Sigma Securities sold out of Zymeworks (ZYME) in Q4 2025, closing a stake of 12,225 shares — an estimated $209K sold.

Two Sigma Securities first reported a position in ZYME in Q3 2025 and held it in 1 quarter. The position peaked at $209K in Q3 2025. 209 funds tracked by Wall St. Rank hold ZYME as of Q4 2025.

Two Sigma Securities reported no remaining Zymeworks position as of Q4 2025 after selling out during the quarter.
Two Sigma Securities sold 12,225 Zymeworks shares in Q4 2025, an estimated $209K.
Two Sigma Securities first reported a position in Zymeworks in Q3 2025 and held it in 1 quarter.
Two Sigma Securities's Zymeworks position peaked at $209K in Q3 2025.
209 funds tracked by Wall St. Rank held Zymeworks as of Q4 2025.

Based on Two Sigma Securities's 13F filing for Q4 2025, filed 17 Feb 2026.