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Two Sigma Securities’s Vertex Pharmaceuticals VRTX Stock Holding History

Two Sigma Securities’s Portfolio VRTX Stock Details VRTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2024
Q4 		– Sell
-8,400
Closed -$3.91M – 3281
2024
Q3 		$3.91M Buy
8,400
+3,500
+71% +$1.68M 0.07% 345
2024
Q2 		$2.3M Buy
4,900
+700
+17% +$304K 0.03% 657
2024
Q1 		$1.76M Buy
4,200
+500
+14% +$211K 0.02% 823
2023
Q4 		$1.51M Sell
3,700
-2,100
-36% -$776K 0.01% 832
2023
Q3 		$2.02M Sell
5,800
-1,800
-24% -$630K 0.02% 683
2023
Q2 		$2.67M Buy
7,600
+2,100
+38% +$708K 0.04% 481
2023
Q1 		$1.73M Buy
5,500
+900
+20% +$270K 0.03% 579
2022
Q4 		$1.33M Buy
4,600
+3,500
+318% +$1.07M 0.04% 564
2022
Q3 		$318K Buy
+1,100
New +$316K 0.01% 1514
2021
Q1 		– Sell
-6,600
Closed -$1.56M – 1785
2020
Q4 		$1.56M Buy
6,600
+4,600
+230% +$1.06M 0.04% 296
2020
Q3 		$544K Sell
2,000
-2,800
-58% -$772K 0.01% 557
2020
Q2 		$1.39M Buy
4,800
+800
+20% +$217K 0.03% 307
2020
Q1 		$952K Sell
4,000
-14,400
-78% -$3.3M 0.02% 400
2019
Q4 		$4.03M Buy
18,400
+1,900
+12% +$385K 0.03% 467
2019
Q3 		$2.79M Buy
16,500
+11,800
+251% +$2.09M 0.03% 479
2019
Q2 		$862K Sell
4,700
-900
-16% -$157K 0.01% 800
2019
Q1 		$1.03M Sell
5,600
-6,900
-55% -$1.27M 0.01% 550
2018
Q4 		$2.07M Sell
12,500
-20,800
-62% -$3.6M 0.03% 354
2018
Q3 		$6.42M Buy
33,300
+1,600
+5% +$285K 0.04% 316
2018
Q2 		$5.39M Sell
31,700
-11,200
-26% -$1.74M 0.03% 476
2018
Q1 		$6.99M Buy
+42,900
New +$7.01M 0.04% 377

Other funds holding VRTX

Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $645B AUM 30.41% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
Capital International Investors
Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Two Sigma Securities's VRTX Position: Q1 2026 in Review

Two Sigma Securities opened a new position in Vertex Pharmaceuticals (VRTX) in Q1 2026: 587 shares worth $262K. The stake represents 0.03% of the portfolio and ranks #867 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in VRTX as recently as Q2 2025.

Two Sigma Securities first reported a position in VRTX in Q1 2016 and has held it in 27 quarters since. The position peaked at $14.6M in Q4 2023. 1,687 funds tracked by Wall St. Rank hold VRTX as of Q1 2026.

  • Two Sigma Securities held 587 shares of Vertex Pharmaceuticals worth $262K as of Q1 2026.
  • Vertex Pharmaceuticals was a new Two Sigma Securities position in Q1 2026.
  • Vertex Pharmaceuticals made up 0.03% of Two Sigma Securities's portfolio in Q1 2026, its #867 holding.
  • Two Sigma Securities first reported a position in Vertex Pharmaceuticals in Q1 2016 and has held it in 27 quarters since.
  • Two Sigma Securities's Vertex Pharmaceuticals position peaked at $14.6M in Q4 2023.
  • 1,687 funds tracked by Wall St. Rank held Vertex Pharmaceuticals as of Q1 2026.

Based on Two Sigma Securities's 13F filing for Q1 2026, filed 15 May 2026.