Two Sigma Securities’s Arrowhead Research ARWR Stock Holding History

Two Sigma Securities’s Portfolio ARWR Stock Details ARWR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$917K	Buy	+11,256	New	+$831K	0.08%	326
2026 Q1	–	Sell	-5,701	Closed	-$378K	–	1645
2025 Q4	$378K	Buy	+5,701	New	+$279K	0.05%	517
2021 Q4	–	Sell	-4,366	Closed	-$273K	–	1537
2021 Q3	$273K	Buy	+4,366	New	+$283K	0.01%	1050
2020 Q1	–	Sell	-4,438	Closed	-$282K	–	1361
2019 Q4	$282K	Buy	+4,438	New	+$220K	﹤0.01%	1839

Other funds holding ARWR

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Norges Bank Oslo, Norway $1T AUM

Invesco Atlanta, Georgia $1.26T AUM 61.52% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

FAM

Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

Two Sigma Securities's ARWR Position: Q2 2026 in Review

Two Sigma Securities opened a new position in Arrowhead Research (ARWR) in Q2 2026: 11,256 shares worth $917K. The stake represents 0.08% of the portfolio and ranks #326 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in ARWR as recently as Q4 2025.

Two Sigma Securities first reported a position in ARWR in Q4 2019 and has held it in 4 quarters since. 500 funds tracked by Wall St. Rank hold ARWR as of Q2 2026.

Two Sigma Securities held 11,256 shares of Arrowhead Research worth $917K as of Q2 2026.
Arrowhead Research was a new Two Sigma Securities position in Q2 2026.
Arrowhead Research made up 0.08% of Two Sigma Securities's portfolio in Q2 2026, its #326 holding.
Two Sigma Securities first reported a position in Arrowhead Research in Q4 2019 and has held it in 4 quarters since.
500 funds tracked by Wall St. Rank held Arrowhead Research as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.