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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.15%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
GBIO
3501
DELISTED
Generation Bio
GBIO
$287K ﹤0.01%
50,557
+38,115
+306% +$215K
FNWD icon
3502
Finward Bancorp
FNWD
$193M
$286K ﹤0.01%
+8,129
New +$286K
RFDA icon
3503
ALPS Dynamic US Dividend Advantage ETF
RFDA
$89.4M
$286K ﹤0.01%
4,480
-1,200
-21% -$75.9K
AVUV icon
3504
Avantis US Small Cap Value ETF
AVUV
$30.9B
$286K ﹤0.01%
2,800
-27,700
-91% -$2.77M
ATNM icon
3505
Actinium Pharmaceuticals
ATNM
$25M
$285K ﹤0.01%
209,692
-24,601
-11% -$35.9K
UPB
3506
Upstream Bio Inc
UPB
$395M
$285K ﹤0.01%
10,500
TSCO icon
3507
PUT
Tractor Supply
TSCO
$18B
$285K ﹤0.01%
+5,700
New +$307K
TCX icon
3508
Tucows
TCX
$175M
$285K ﹤0.01%
12,714
-6,921
-35% -$141K
BZUN
3509
Baozun
BZUN
$172M
$284K ﹤0.01%
+106,579
New +$335K
LBRX
3510
LB Pharmaceuticals
LBRX
$1.38B
$283K ﹤0.01%
12,720
-780
-6% -$13.6K
JILL icon
3511
J. Jill
JILL
$283M
$283K ﹤0.01%
20,594
+81
+0.4% +$1.22K
SNCR
3512
DELISTED
Synchronoss Technologies
SNCR
$281K ﹤0.01%
32,803
-37,093
-53% -$229K
ARE icon
3513
Alexandria Real Estate Equities
ARE
$8.56B
$280K ﹤0.01%
+5,720
New +$337K
HRB icon
3514
PUT
H&R Block
HRB
$5.86B
$279K ﹤0.01%
+6,400
New +$299K
AAOI icon
3515
PUT
Applied Optoelectronics
AAOI
$11.5B
$279K ﹤0.01%
+8,000
New +$239K
HUSV icon
3516
First Trust Horizon Managed Volatility Domestic ETF
HUSV
$74.8M
$279K ﹤0.01%
7,200
-1,500
-17% -$58.4K
AYTU icon
3517
AYTU BioPharma
AYTU
$25.3M
$279K ﹤0.01%
107,133
+38,397
+56% +$86.1K
BRLT icon
3518
Brilliant Earth
BRLT
$21.6M
$278K ﹤0.01%
158,898
+10,283
+7% +$21.9K
CLAR icon
3519
Clarus
CLAR
$143M
$277K ﹤0.01%
82,657
+19,503
+31% +$66.4K
BLNK icon
3520
Blink Charging
BLNK
$87.9M
$277K ﹤0.01%
414,726
+228,082
+122% +$330K
ACIU icon
3521
AC Immune
ACIU
$240M
$276K ﹤0.01%
87,884
+71,109
+424% +$224K
AZN icon
3522
CALL
AstraZeneca
AZN
$250B
$276K ﹤0.01%
+1,500
New +$263K
CIGI icon
3523
Colliers International
CIGI
$5.19B
$275K ﹤0.01%
1,874
-14,200
-88% -$2.13M
NETL icon
3524
Colterpoint Net Lease Real Estate ETF
NETL
$54.3M
$275K ﹤0.01%
11,600
-3,300
-22% -$79.7K
CCJ icon
3525
CALL
Cameco
CCJ
$42.4B
$274K ﹤0.01%
+3,000
New +$270K

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Two Sigma Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Two Sigma Investments held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

Two Sigma Investments's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • Two Sigma Investments's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • Two Sigma Investments added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • Two Sigma Investments's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • Two Sigma Investments fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • Two Sigma Investments's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • Two Sigma Investments opened 899 new positions and closed 504 in Q4 2025.
  • Two Sigma Investments's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.