Two Sigma Investments
TNYA icon

Two Sigma Investments’s Tenaya Therapeutics TNYA Stock Holding History

Two Sigma Investments’s Portfolio TNYA Stock Details TNYA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$887K Buy
1,280,390
+14,315
+1% +$10.6K ﹤0.01% 3354
2025
Q4 		$901K Buy
1,266,075
+355,507
+39% +$483K ﹤0.01% 2996
2025
Q3 		$1.48M Buy
910,568
+435,781
+92% +$439K ﹤0.01% 2331
2025
Q2 		$290K Buy
474,787
+107,158
+29% +$54.5K ﹤0.01% 2801
2025
Q1 		$210K Buy
367,629
+322,858
+721% +$319K ﹤0.01% 2837
2024
Q4 		$64K Sell
44,771
-9,943
-18% -$22.3K ﹤0.01% 3021
2024
Q3 		$106K Sell
54,714
-52,865
-49% -$149K ﹤0.01% 2894
2024
Q2 		$333K Sell
107,579
-766
-0.7% -$3.16K ﹤0.01% 2546
2024
Q1 		$567K Sell
108,345
-81,536
-43% -$390K ﹤0.01% 2274
2023
Q4 		$615K Sell
189,881
-61,705
-25% -$133K ﹤0.01% 2353
2023
Q3 		$642K Buy
251,586
+8,987
+4% +$37.6K ﹤0.01% 2166
2023
Q2 		$1.42M Buy
242,599
+123,876
+104% +$720K ﹤0.01% 1726
2023
Q1 		$338K Buy
118,723
+38,505
+48% +$108K ﹤0.01% 2372
2022
Q4 		$161K Buy
80,218
+46,919
+141% +$115K ﹤0.01% 2433
2022
Q3 		$97K Buy
+33,299
New +$155K ﹤0.01% 2239

Other funds holding TNYA

VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
EAM
Empery Asset Management New York $83M AUM
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
BGM
Burkehill Global Management New York $2.02B AUM 85.32% 1-Year Est. Return
KCM
Kalehua Capital Management Dallas, Texas $141M AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Two Sigma Investments's TNYA Position: Q1 2026 in Review

Two Sigma Investments increased its Tenaya Therapeutics (TNYA) stake by 1.1% in Q1 2026, buying an estimated $10.6K and bringing the position to 1,280,390 shares worth $887K. The position accounts for ﹤0.01% of the portfolio, ranked #3354.

Two Sigma Investments first reported a position in TNYA in Q3 2022 and has held it in 15 quarters since. The position peaked at $1.48M in Q3 2025. 103 funds tracked by Wall St. Rank hold TNYA as of Q1 2026.

  • Two Sigma Investments held 1,280,390 shares of Tenaya Therapeutics worth $887K as of Q1 2026.
  • Two Sigma Investments bought 14,315 Tenaya Therapeutics shares in Q1 2026, an estimated $10.6K.
  • Tenaya Therapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3354 holding.
  • Two Sigma Investments first reported a position in Tenaya Therapeutics in Q3 2022 and has held it in 15 quarters since.
  • Two Sigma Investments's Tenaya Therapeutics position peaked at $1.48M in Q3 2025.
  • 103 funds tracked by Wall St. Rank held Tenaya Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.