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Tenaya Therapeutics

103 hedge funds and large institutions have $37.5M invested in Tenaya Therapeutics in 2026 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 32 increasing their positions, 18 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

750% more call options, than puts

Call options by funds: $408K | Put options by funds: $48K

78% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 18

37% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 19

6% more funds holding

Funds holding: 97103 (+6)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

16.2% less ownership

Funds ownership: 41.22%25.03% (-16%)

23% less capital invested

Capital invested by funds: $48.8M → $37.5M (-$11.3M)

Holders
103
Holders Change
+6
Holders Change %
+6.19%
% of All Funds
1.27%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
26
Increased
32
Reduced
18
Closed
19
Calls
$408K
Puts
$48K
Net Calls
+$360K
Net Calls Change
-$13K
Name Holding Trade Value Shares
Change
Change in
Stake
VCM
1
Vanguard Capital Management
Pennsylvania
$5.87M +$6.26M +8,482,288 New
Millennium Management
2
Millennium Management
New York
$3.78M +$621K +840,920 +18%
EAM
3
Empery Asset Management
New York
$2.97M -$832K -1,127,168 -21%
Citadel Advisors
4
Citadel Advisors
Florida
$2.91M
Renaissance Technologies
5
Renaissance Technologies
New York
$2.57M +$1.37M +1,862,894 +101%
BlackRock
6
BlackRock
New York
$2.56M -$181K -244,631 -6%
Marshall Wace
7
Marshall Wace
United Kingdom
$1.87M +$959K +1,299,355 +92%
BGM
8
Burkehill Global Management
New York
$1.38M
KCM
9
Kalehua Capital Management
Texas
$1.38M
Geode Capital Management
10
Geode Capital Management
Massachusetts
$1.08M +$271K +366,584 +31%
ACM
11
ADAR1 Capital Management
Texas
$1.04M +$1.84K +2,500 +0.2%
Two Sigma Investments
12
Two Sigma Investments
New York
$887K +$10.6K +14,315 +1%
Jane Street
13
Jane Street
New York
$817K +$370K +501,621 +74%
GCP
14
GSA Capital Partners
United Kingdom
$743K -$299K -405,701 -27%
EC
15
Euclidean Capital
New York
$703K
VFT
16
Vanguard Fiduciary Trust
Pennsylvania
$703K +$750K +1,015,702 New
AI
17
Alphabet Inc
California
$632K
RBI
18
Raiffeisen Bank International
Austria
$620K +$73.8K +100,000 +11%
MCP
19
Mirador Capital Partners
California
$614K +$225K +304,393 +52%
State Street
20
State Street
Massachusetts
$491K +$194K +262,900 +59%
UBS Group
21
UBS Group
Switzerland
$460K +$63.2K +85,579 +15%
SG
22
StepStone Group
California
$319K
CC
23
Casdin Capital
New York
$251K
Squarepoint
24
Squarepoint
New York
$241K +$257K +348,268 New
Northern Trust
25
Northern Trust
Illinois
$215K +$51K +69,074 +29%

TNYA Hedge Fund Activity: Q1 2026 in Review

103 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Tenaya Therapeutics (TNYA) for Q1 2026, worth a combined $37.5M — down 23% from $48.8M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new TNYA positions and 19 closed out — a net gain of 7 holders — while 32 added to existing stakes and 18 trimmed.

The largest buyer was Renaissance Technologies, adding an estimated $1.37M. The largest seller was Column Group, exiting entirely with an estimated $6.69M sold.

  • 103 institutional investors held Tenaya Therapeutics (TNYA) as of Q1 2026, up from 97 in Q4 2025.
  • Funds reported $37.5M of Tenaya Therapeutics stock for Q1 2026, down 23% quarter-over-quarter.
  • 26 funds opened new Tenaya Therapeutics positions in Q1 2026 and 19 closed out, a net change of +7 holders.
  • The largest Tenaya Therapeutics buyer in Q1 2026 was Renaissance Technologies, an estimated $1.37M added.
  • The largest Tenaya Therapeutics seller in Q1 2026 was Column Group, an estimated $6.69M sold.

Based on aggregated 13F filings for Q1 2026.