Two Sigma Investments
RNAM

Two Sigma Investments’s Avidity Biosciences RNAM Stock Holding History

Two Sigma Investments’s Portfolio RNAM Stock Details RNAM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q2 		– Sell
-28,000
Closed -$827K – 3485
2025
Q1 		$827K Sell
28,000
-104,560
-79% -$3.26M ﹤0.01% 2283
2024
Q4 		$3.85M Buy
132,560
+2,465
+2% +$103K 0.01% 1267
2024
Q3 		$5.98M Sell
130,095
-95,651
-42% -$4.15M 0.01% 994
2024
Q2 		$9.22M Sell
225,746
-21,554
-9% -$618K 0.02% 743
2024
Q1 		$6.31M Sell
247,300
-420,233
-63% -$6.59M 0.01% 850
2023
Q4 		$6.04M Buy
667,533
+104,191
+18% +$696K 0.01% 888
2023
Q3 		$3.59M Buy
563,342
+48,521
+9% +$418K 0.01% 1063
2023
Q2 		$5.71M Buy
514,821
+186,333
+57% +$2.34M 0.01% 867
2023
Q1 		$5.04M Buy
328,488
+221,588
+207% +$4.88M 0.01% 908
2022
Q4 		$2.37M Buy
106,900
+86,491
+424% +$1.29M 0.01% 1227
2022
Q3 		$333K Buy
+20,409
New +$390K ﹤0.01% 1929
2021
Q4 		– Sell
-13,900
Closed -$342K – 4789
2021
Q3 		$342K Buy
+13,900
New +$302K ﹤0.01% 3561

Other funds holding RNAM

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Two Sigma Investments's RNAM Position: Q2 2025 in Review

Two Sigma Investments sold out of Avidity Biosciences (RNAM) in Q2 2025, closing a stake of 28,000 shares — an estimated $827K sold.

Two Sigma Investments first reported a position in RNAM in Q3 2021 and held it in 12 quarters. The position peaked at $9.22M in Q2 2024. 206 funds tracked by Wall St. Rank hold RNAM as of Q2 2025.

  • Two Sigma Investments reported no remaining Avidity Biosciences position as of Q2 2025 after selling out during the quarter.
  • Two Sigma Investments sold 28,000 Avidity Biosciences shares in Q2 2025, an estimated $827K.
  • Two Sigma Investments first reported a position in Avidity Biosciences in Q3 2021 and held it in 12 quarters.
  • Two Sigma Investments's Avidity Biosciences position peaked at $9.22M in Q2 2024.
  • 206 funds tracked by Wall St. Rank held Avidity Biosciences as of Q2 2025.

Based on Two Sigma Investments's 13F filing for Q2 2025, filed 14 Aug 2025.