Two Sigma Investments
PLX icon

Two Sigma Investments’s Protalix BioTherapeutics PLX Stock Holding History

Two Sigma Investments’s Portfolio PLX Stock Details PLX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$39.3K Buy
+18,129
New +$45K ﹤0.01% 4473
2025
Q3 		– Sell
-71,537
Closed -$106K – 3859
2025
Q2 		$106K Sell
71,537
-14,817
-17% -$30.3K ﹤0.01% 2990
2025
Q1 		$221K Buy
+86,354
New +$206K ﹤0.01% 2824
2024
Q1 		– Sell
-19,600
Closed -$34.9K – 3298
2023
Q4 		$34.9K Sell
19,600
-27,700
-59% -$43.1K ﹤0.01% 3025
2023
Q3 		$78.5K Sell
47,300
-7,825
-14% -$14K ﹤0.01% 2767
2023
Q2 		$110K Sell
55,125
-138,969
-72% -$331K ﹤0.01% 2743
2023
Q1 		$408K Buy
194,094
+183,968
+1,817% +$323K ﹤0.01% 2294
2022
Q4 		$13.9K Sell
10,126
-225
-2% -$247 ﹤0.01% 2711
2022
Q3 		$11K Sell
10,351
-15,159
-59% -$16.8K ﹤0.01% 2414
2022
Q2 		$28K Buy
+25,510
New +$29.8K ﹤0.01% 2382
2015
Q1 		– Sell
-4,021
Closed -$74K – 2803
2014
Q4 		$74K Buy
4,021
+1,139
+40% +$24.5K ﹤0.01% 2147
2014
Q3 		$70K Sell
2,882
-912
-24% -$26.3K ﹤0.01% 1683
2014
Q2 		$138K Buy
+3,794
New +$153K ﹤0.01% 2027
2014
Q1 		– Sell
-5,357
Closed -$208K – 2199
2013
Q4 		$208K Buy
5,357
+3,487
+186% +$147K ﹤0.01% 2001
2013
Q3 		$85K Sell
1,870
-1,726
-48% -$88.6K ﹤0.01% 1761
2013
Q2 		$177K Buy
+3,596
New +$191K ﹤0.01% 1805

Other funds holding PLX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
MCO
MAK Capital One New York $679M AUM 29.02% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Northern Trust
Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
SWP
Stratos Wealth Partners Beachwood, Ohio $8.8B AUM 21.82% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
PFS
Prospera Financial Services Dallas, Texas $6.89B AUM 37.41% 1-Year Est. Return
OM
Opaleye Management Boston, Massachusetts $759M AUM 124.8% 1-Year Est. Return

Two Sigma Investments's PLX Position: Q1 2026 in Review

Two Sigma Investments opened a new position in Protalix BioTherapeutics (PLX) in Q1 2026: 18,129 shares worth $39.3K. The stake represents ﹤0.01% of the portfolio and ranks #4473 among its holdings. This is a return to the name: Two Sigma Investments previously reported a position in PLX as recently as Q2 2025.

Two Sigma Investments first reported a position in PLX in Q2 2013 and has held it in 16 quarters since. The position peaked at $408K in Q1 2023. 99 funds tracked by Wall St. Rank hold PLX as of Q1 2026.

  • Two Sigma Investments held 18,129 shares of Protalix BioTherapeutics worth $39.3K as of Q1 2026.
  • Protalix BioTherapeutics was a new Two Sigma Investments position in Q1 2026.
  • Protalix BioTherapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #4473 holding.
  • Two Sigma Investments first reported a position in Protalix BioTherapeutics in Q2 2013 and has held it in 16 quarters since.
  • Two Sigma Investments's Protalix BioTherapeutics position peaked at $408K in Q1 2023.
  • 99 funds tracked by Wall St. Rank held Protalix BioTherapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.