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Protalix BioTherapeutics

63 hedge funds and large institutions have $21M invested in Protalix BioTherapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 19 increasing their positions, 10 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

405% more call options, than puts

Call options by funds: $838K | Put options by funds: $166K

360% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 5

150% more capital invested

Capital invested by funds: $8.4M → $21M (+$12.6M)

90% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 10

40% more funds holding

Funds holding: 4563 (+18)

4.52% more ownership

Funds ownership: 5.97%10.49% (+4.5%)

Holders
63
Holders Change
+18
Holders Change %
+40%
% of All Funds
0.84%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
23
Increased
19
Reduced
10
Closed
5
Calls
$838K
Puts
$166K
Net Calls
+$672K
Net Calls Change
+$584K
Name Holding Trade Value Shares
Change
Change in
Stake
Renaissance Technologies
1
Renaissance Technologies
New York
$3.04M +$169K +70,953 +6%
Millennium Management
2
Millennium Management
New York
$2.47M +$1.37M +575,090 +148%
Susquehanna International Group
3
Susquehanna International Group
Pennsylvania
$2.2M +$2.05M +858,650 New
Northern Trust
4
Northern Trust
Illinois
$1.75M -$112K -46,984 -6%
Marshall Wace
5
Marshall Wace
United Kingdom
$1.57M +$1.23M +513,186 +504%
Connor, Clark & Lunn Investment Management (CC&L)
6
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.24M +$1.15M +482,875 New
SWP
7
Stratos Wealth Partners
Ohio
$887K +$182K +76,400 +28%
Jane Street
8
Jane Street
New York
$753K +$432K +180,702 +159%
Goldman Sachs
9
Goldman Sachs
New York
$741K +$573K +239,751 +482%
BlackRock
10
BlackRock
New York
$652K +$71.3K +29,878 +13%
GCP
11
GSA Capital Partners
United Kingdom
$536K -$230K -96,457 -32%
BCM
12
Bridgeway Capital Management
Texas
$484K +$18.4K +7,700 +4%
OAC
13
OMERS Administration Corp
Ontario, Canada
$459K +$428K +179,300 New
SSA
14
Schonfeld Strategic Advisors
New York
$417K +$389K +163,058 New
Squarepoint
15
Squarepoint
New York
$309K +$112K +46,846 +63%
Qube Research & Technologies (QRT)
16
Qube Research & Technologies (QRT)
United Kingdom
$304K +$224K +93,941 +378%
HIM
17
Hillsdale Investment Management
Ontario, Canada
$297K +$277K +116,100 New
Two Sigma Investments
18
Two Sigma Investments
New York
$221K +$206K +86,354 New
Morgan Stanley
19
Morgan Stanley
New York
$214K -$207K -86,658 -51%
JG
20
Jain Global
New York
$210K +$196K +81,963 New
Balyasny Asset Management
21
Balyasny Asset Management
Illinois
$195K +$182K +76,063 New
PAS
22
Point72 Asia (Singapore)
Singapore
$139K +$1.59K +667 +1%
CSS
23
Cubist Systematic Strategies
Connecticut
$137K +$57.5K +24,073 +82%
QC
24
Quantessence Capital
New York
$131K +$122K +51,243 New
Commonwealth Equity Services
25
Commonwealth Equity Services
Massachusetts
$128K +$60 +25 +0.1%

PLX Hedge Fund Activity: Q1 2025 in Review

63 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Protalix BioTherapeutics (PLX) for Q1 2025, worth a combined $21M — up 150% from $8.4M a quarter earlier.

Buyers outnumbered sellers: 23 funds opened new PLX positions and 5 closed out — a net gain of 18 holders — while 19 added to existing stakes and 10 trimmed.

The largest buyer was Susquehanna International Group, opening a new position worth an estimated $2.05M. The largest seller was Citadel Advisors, cutting an estimated $341K.

  • 63 institutional investors held Protalix BioTherapeutics (PLX) as of Q1 2025, up from 45 in Q4 2024.
  • Funds reported $21M of Protalix BioTherapeutics stock for Q1 2025, up 150% quarter-over-quarter.
  • 23 funds opened new Protalix BioTherapeutics positions in Q1 2025 and 5 closed out, a net change of +18 holders.
  • The largest Protalix BioTherapeutics buyer in Q1 2025 was Susquehanna International Group, an estimated $2.05M added.
  • The largest Protalix BioTherapeutics seller in Q1 2025 was Citadel Advisors, an estimated $341K sold.

Based on aggregated 13F filings for Q1 2025.