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Protalix BioTherapeutics
PLX

Overview Fund Activity

63 hedge funds and large institutions have $21M invested in Protalix BioTherapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 19 increasing their positions, 10 reducing their positions, and 5 closing their positions.

Holders
63
Holders Change
+18
Holders Change %
+40%
% of All Funds
0.86%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
23
Increased
19
Reduced
10
Closed
5
Calls
$838K
Puts
$166K
Net Calls
+$672K
Net Calls Change
+$584K

Top Buyers

1
Susquehanna International Group
1
Susquehanna International Group
Pennsylvania
$2.2M
2
Millennium Management
2
Millennium Management
New York
$2.47M
3
Marshall Wace
3
Marshall Wace
United Kingdom
$1.57M
4
Connor, Clark & Lunn Investment Management (CC&L)
4
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.24M
5
Goldman Sachs
5
Goldman Sachs
New York
$741K

Top Sellers

1
Citadel Advisors
1
Citadel Advisors
Florida
$7.21K
2
GCP
2
GSA Capital Partners
United Kingdom
$536K
3
Morgan Stanley
3
Morgan Stanley
New York
$214K
4
Northern Trust
4
Northern Trust
Illinois
$1.75M
5
Bank of America
5
Bank of America
North Carolina
$16
Name Market Value Shares Shares
Change 		Shares
Change %
Renaissance Technologies
1
Renaissance Technologies
New York
$3.04M 1,188,953 +70,953 +6%
Millennium Management
2
Millennium Management
New York
$2.47M 963,011 +575,090 +148%
Susquehanna International Group
3
Susquehanna International Group
Pennsylvania
$2.2M 858,650 +858,650 New
Northern Trust
4
Northern Trust
Illinois
$1.75M 684,758 -46,984 -6%
Marshall Wace
5
Marshall Wace
United Kingdom
$1.57M 615,085 +513,186 +504%
Connor, Clark & Lunn Investment Management (CC&L)
6
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.24M 482,875 +482,875 New
SWP
7
Stratos Wealth Partners
Ohio
$887K 346,400 +76,400 +28%
Jane Street
8
Jane Street
New York
$753K 294,318 +180,702 +159%
Goldman Sachs
9
Goldman Sachs
New York
$741K 289,461 +239,751 +482%
BlackRock
10
BlackRock
New York
$652K 254,535 +29,878 +13%
GCP
11
GSA Capital Partners
United Kingdom
$536K 209,292 -96,457 -32%
BCM
12
Bridgeway Capital Management
Texas
$484K 189,100 +7,700 +4%
OAC
13
OMERS Administration Corp
Ontario, Canada
$459K 179,300 +179,300 New
SSA
14
Schonfeld Strategic Advisors
New York
$417K 163,058 +163,058 New
Squarepoint
15
Squarepoint
New York
$309K 120,786 +46,846 +63%
Qube Research & Technologies (QRT)
16
Qube Research & Technologies (QRT)
United Kingdom
$304K 118,808 +93,941 +378%
HIM
17
Hillsdale Investment Management
Ontario, Canada
$297K 116,100 +116,100 New
Two Sigma Investments
18
Two Sigma Investments
New York
$221K 86,354 +86,354 New
Morgan Stanley
19
Morgan Stanley
New York
$214K 83,558 -86,658 -51%
JG
20
Jain Global
New York
$210K 81,963 +81,963 New
Balyasny Asset Management
21
Balyasny Asset Management
Illinois
$195K 76,063 +76,063 New
PAS
22
Point72 Asia (Singapore)
Singapore
$139K 54,174 +667 +1%
CSS
23
Cubist Systematic Strategies
Connecticut
$137K 53,380 +24,073 +82%
QC
24
Quantessence Capital
New York
$131K 51,243 +51,243 New
Commonwealth Equity Services
25
Commonwealth Equity Services
Massachusetts
$128K 50,025 +25 +0.1%
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