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Protalix BioTherapeutics

63 hedge funds and large institutions have $17.6M invested in Protalix BioTherapeutics in 2025 Q2 according to their latest regulatory filings, with 30 funds opening new positions, 20 increasing their positions, 3 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

567% more repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 3

553% more call options, than puts

Call options by funds: $379K | Put options by funds: $58K

4.47% more ownership

Funds ownership: 10.49%14.96% (+4.5%)

0% more funds holding

Funds holding: 6363 (0)

0% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 30

16% less capital invested

Capital invested by funds: $21M → $17.6M (-$3.33M)

Holders
63
Holders Change
Holders Change %
0%
% of All Funds
0.83%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
30
Increased
20
Reduced
3
Closed
30
Calls
$379K
Puts
$58K
Net Calls
+$321K
Net Calls Change
-$351K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$4.99M +$6.37M +3,115,135 +1,224%
Renaissance Technologies
2
Renaissance Technologies
New York
$2.39M +$872K +426,050 +36%
Northern Trust
3
Northern Trust
Illinois
$1.6M +$808K +394,965 +58%
Geode Capital Management
4
Geode Capital Management
Massachusetts
$1.22M +$1.69M +826,333 New
Connor, Clark & Lunn Investment Management (CC&L)
5
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$734K +$27.3K +13,341 +3%
Vanguard Group
6
Vanguard Group
Pennsylvania
$718K +$992K +484,798 New
Morgan Stanley
7
Morgan Stanley
New York
$684K +$774K +378,485 +453%
State Street
8
State Street
Massachusetts
$657K +$909K +444,239 New
SWP
9
Stratos Wealth Partners
Ohio
$518K +$7.37K +3,600 +1%
Susquehanna International Group
10
Susquehanna International Group
Pennsylvania
$442K -$1.15M -560,083 -65%
Commonwealth Equity Services
11
Commonwealth Equity Services
Massachusetts
$291K +$300K +146,772 +293%
BCM
12
Bridgeway Capital Management
Texas
$280K
Charles Schwab
13
Charles Schwab
California
$259K +$358K +175,070 New
ECM
14
Evergreen Capital Management
Washington
$254K +$351K +171,338 New
DC
15
Diametric Capital
Massachusetts
$212K +$293K +143,272 New
Bank of New York Mellon
16
Bank of New York Mellon
New York
$199K +$275K +134,287 New
Barclays
17
Barclays
United Kingdom
$188K +$210K +102,653 +422%
HIM
18
Hillsdale Investment Management
Ontario, Canada
$175K +$4.09K +2,000 +2%
Goldman Sachs
19
Goldman Sachs
New York
$151K -$383K -187,283 -65%
N
20
Nuveen
North Carolina
$133K +$185K +90,188 New
UBS Group
21
UBS Group
Switzerland
$111K +$149K +73,063 +3,501%
XT
22
XTX Topco
Cayman Islands
$109K +$65.2K +31,849 +76%
Two Sigma Investments
23
Two Sigma Investments
New York
$106K -$30.3K -14,817 -17%
RhumbLine Advisers
24
RhumbLine Advisers
Massachusetts
$103K +$143K +69,796 New
New York State Common Retirement Fund
25
New York State Common Retirement Fund
New York
$102K +$141K +69,000 New

PLX Hedge Fund Activity: Q2 2025 in Review

63 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Protalix BioTherapeutics (PLX) for Q2 2025, worth a combined $17.6M — down 16% from $21M a quarter earlier.

Fund positioning in PLX was balanced in Q2 2025: 30 funds opened new positions, 30 closed out, 20 added to existing stakes and 3 trimmed.

The largest buyer was BlackRock, adding an estimated $6.37M. The largest seller was Millennium Management, exiting entirely with an estimated $2.47M sold.

  • 63 institutional investors held Protalix BioTherapeutics (PLX) as of Q2 2025, unchanged from Q1 2025.
  • Funds reported $17.6M of Protalix BioTherapeutics stock for Q2 2025, down 16% quarter-over-quarter.
  • 30 funds opened new Protalix BioTherapeutics positions in Q2 2025 and 30 closed out, a net change of 0 holders.
  • The largest Protalix BioTherapeutics buyer in Q2 2025 was BlackRock, an estimated $6.37M added.
  • The largest Protalix BioTherapeutics seller in Q2 2025 was Millennium Management, an estimated $2.47M sold.

Based on aggregated 13F filings for Q2 2025.