Two Sigma Investments
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Two Sigma Investments’s Mirum Pharmaceuticals MIRM Stock Holding History

Two Sigma Investments’s Portfolio MIRM Stock Details MIRM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$80.8M Sell
690,318
-84,523
-11% -$8.49M 0.06% 382
2026
Q1 		$71.6M Buy
774,841
+386,299
+99% +$36.3M 0.06% 375
2025
Q4 		$30.7M Buy
388,542
+45,416
+13% +$3.26M 0.04% 532
2025
Q3 		$25.2M Buy
343,126
+171,312
+100% +$10.9M 0.04% 552
2025
Q2 		$8.74M Sell
171,814
-3,312
-2% -$147K 0.02% 888
2025
Q1 		$7.89M Buy
175,126
+48,680
+38% +$2.29M 0.02% 869
2024
Q4 		$5.23M Sell
126,446
-101,027
-44% -$4.21M 0.01% 1077
2024
Q3 		$8.87M Buy
227,473
+63,933
+39% +$2.55M 0.02% 819
2024
Q2 		$5.59M Buy
163,540
+8,187
+5% +$215K 0.01% 958
2024
Q1 		$3.9M Sell
155,353
-40,775
-21% -$1.12M 0.01% 1106
2023
Q4 		$5.79M Sell
196,128
-132,656
-40% -$4.01M 0.01% 909
2023
Q3 		$10.4M Buy
328,784
+225,674
+219% +$6.18M 0.03% 599
2023
Q2 		$2.67M Buy
+103,110
New +$2.74M 0.01% 1257
2022
Q4 		– Sell
-47,748
Closed -$1M – 2970
2022
Q3 		$1M Sell
47,748
-73,544
-61% -$1.77M ﹤0.01% 1470
2022
Q2 		$2.36M Sell
121,292
-74,587
-38% -$1.76M 0.01% 1107
2022
Q1 		$4.31M Buy
195,879
+25,902
+15% +$528K 0.01% 986
2021
Q4 		$2.71M Buy
169,977
+14,702
+9% +$229K 0.01% 1652
2021
Q3 		$3.09M Buy
155,275
+61,360
+65% +$998K 0.01% 1587
2021
Q2 		$1.62M Sell
93,915
-2,105
-2% -$37.7K ﹤0.01% 2054
2021
Q1 		$1.9M Buy
96,020
+81,020
+540% +$1.55M 0.01% 1747
2020
Q4 		$262K Sell
15,000
-37,783
-72% -$743K ﹤0.01% 2960
2020
Q3 		$1.02M Buy
52,783
+7,990
+18% +$171K ﹤0.01% 1747
2020
Q2 		$872K Buy
+44,793
New +$749K ﹤0.01% 1625

Other funds holding MIRM

FLSM
Frazier Life Sciences Management Palo Alto, California $4.59B AUM 237.58% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
William Blair Investment Management
William Blair Investment Management Chicago, Illinois $33.3B AUM 44.76% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

Two Sigma Investments's MIRM Position: Q2 2026 in Review

Two Sigma Investments reduced its Mirum Pharmaceuticals (MIRM) stake by 11% in Q2 2026, selling an estimated $8.49M and leaving 690,318 shares worth $80.8M. The position accounts for 0.06% of the portfolio, ranked #382.

Two Sigma Investments first reported a position in MIRM in Q2 2020 and has held it in 23 quarters since. 328 funds tracked by Wall St. Rank hold MIRM as of Q2 2026.

  • Two Sigma Investments held 690,318 shares of Mirum Pharmaceuticals worth $80.8M as of Q2 2026.
  • Two Sigma Investments sold 84,523 Mirum Pharmaceuticals shares in Q2 2026, an estimated $8.49M.
  • Mirum Pharmaceuticals made up 0.06% of Two Sigma Investments's portfolio in Q2 2026, its #382 holding.
  • Two Sigma Investments first reported a position in Mirum Pharmaceuticals in Q2 2020 and has held it in 23 quarters since.
  • 328 funds tracked by Wall St. Rank held Mirum Pharmaceuticals as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.