Two Sigma Investments
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Two Sigma Investments’s Mirum Pharmaceuticals MIRM Stock Holding History

Two Sigma Investments’s Portfolio MIRM Stock Details MIRM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$71.6M Buy
774,841
+386,299
+99% +$36.3M 0.06% 375
2025
Q4 		$30.7M Buy
388,542
+45,416
+13% +$3.26M 0.04% 532
2025
Q3 		$25.2M Buy
343,126
+171,312
+100% +$10.9M 0.04% 552
2025
Q2 		$8.74M Sell
171,814
-3,312
-2% -$147K 0.02% 888
2025
Q1 		$7.89M Buy
175,126
+48,680
+38% +$2.29M 0.02% 869
2024
Q4 		$5.23M Sell
126,446
-101,027
-44% -$4.21M 0.01% 1077
2024
Q3 		$8.87M Buy
227,473
+63,933
+39% +$2.55M 0.02% 819
2024
Q2 		$5.59M Buy
163,540
+8,187
+5% +$215K 0.01% 958
2024
Q1 		$3.9M Sell
155,353
-40,775
-21% -$1.12M 0.01% 1106
2023
Q4 		$5.79M Sell
196,128
-132,656
-40% -$4.01M 0.01% 909
2023
Q3 		$10.4M Buy
328,784
+225,674
+219% +$6.18M 0.03% 599
2023
Q2 		$2.67M Buy
+103,110
New +$2.74M 0.01% 1257
2022
Q4 		– Sell
-47,748
Closed -$1M – 2970
2022
Q3 		$1M Sell
47,748
-73,544
-61% -$1.77M ﹤0.01% 1470
2022
Q2 		$2.36M Sell
121,292
-74,587
-38% -$1.76M 0.01% 1107
2022
Q1 		$4.31M Buy
195,879
+25,902
+15% +$528K 0.01% 986
2021
Q4 		$2.71M Buy
169,977
+14,702
+9% +$229K 0.01% 1652
2021
Q3 		$3.09M Buy
155,275
+61,360
+65% +$998K 0.01% 1587
2021
Q2 		$1.62M Sell
93,915
-2,105
-2% -$37.7K ﹤0.01% 2054
2021
Q1 		$1.9M Buy
96,020
+81,020
+540% +$1.55M 0.01% 1747
2020
Q4 		$262K Sell
15,000
-37,783
-72% -$743K ﹤0.01% 2960
2020
Q3 		$1.02M Buy
52,783
+7,990
+18% +$171K ﹤0.01% 1747
2020
Q2 		$872K Buy
+44,793
New +$749K ﹤0.01% 1625

Other funds holding MIRM

FLSM
Frazier Life Sciences Management Palo Alto, California $3.89B AUM 201.1% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
EAM
Eventide Asset Management Boston, Massachusetts $6.05B AUM 76.64% 1-Year Est. Return

Two Sigma Investments's MIRM Position: Q1 2026 in Review

Two Sigma Investments increased its Mirum Pharmaceuticals (MIRM) stake by 99% in Q1 2026, buying an estimated $36.3M and bringing the position to 774,841 shares worth $71.6M. The position accounts for 0.06% of the portfolio, ranked #375.

Two Sigma Investments first reported a position in MIRM in Q2 2020 and has held it in 22 quarters since. 311 funds tracked by Wall St. Rank hold MIRM as of Q1 2026.

  • Two Sigma Investments held 774,841 shares of Mirum Pharmaceuticals worth $71.6M as of Q1 2026.
  • Two Sigma Investments bought 386,299 Mirum Pharmaceuticals shares in Q1 2026, an estimated $36.3M.
  • Mirum Pharmaceuticals made up 0.06% of Two Sigma Investments's portfolio in Q1 2026, its #375 holding.
  • Two Sigma Investments first reported a position in Mirum Pharmaceuticals in Q2 2020 and has held it in 22 quarters since.
  • 311 funds tracked by Wall St. Rank held Mirum Pharmaceuticals as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.