Two Sigma Investments
LONA

Two Sigma Investments’s LeonaBio Inc LONA Stock Holding History

Two Sigma Investments’s Portfolio LONA Stock Details LONA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$122K Hold
13,276
– – ﹤0.01% 4865
2026
Q1 		$136K Buy
13,276
+2,530
+24% +$16.5K ﹤0.01% 4349
2025
Q4 		$81.3K Buy
+10,746
New +$49.2K ﹤0.01% 3877
2024
Q4 		– Sell
-25,847
Closed -$115K – 3202
2024
Q3 		$115K Sell
25,847
-4,366
-14% -$102K ﹤0.01% 2884
2024
Q2 		$801K Sell
30,213
-12,348
-29% -$291K ﹤0.01% 2108
2024
Q1 		$1.17M Buy
42,561
+12,154
+40% +$386K ﹤0.01% 1854
2023
Q4 		$739K Buy
30,407
+3,702
+14% +$65.7K ﹤0.01% 2242
2023
Q3 		$539K Sell
26,705
-8,964
-25% -$230K ﹤0.01% 2237
2023
Q2 		$1.05M Sell
35,669
-6,472
-15% -$184K ﹤0.01% 1919
2023
Q1 		$1.05M Buy
42,141
+8,107
+24% +$261K ﹤0.01% 1843
2022
Q4 		$1.08M Sell
34,034
-2,030
-6% -$64K ﹤0.01% 1656
2022
Q3 		$1.07M Buy
36,064
+8,221
+30% +$284K ﹤0.01% 1432
2022
Q2 		$849K Buy
27,843
+21,017
+308% +$1.93M ﹤0.01% 1612
2022
Q1 		$921K Sell
6,826
-9,362
-58% -$987K ﹤0.01% 1744
2021
Q4 		$2.11M Sell
16,188
-6,132
-27% -$775K ﹤0.01% 1872
2021
Q3 		$2.09M Buy
22,320
+14,440
+183% +$1.47M ﹤0.01% 1948
2021
Q2 		$807K Buy
+7,880
New +$1.38M ﹤0.01% 2669

Other funds holding LONA

PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return
ACA
Acorn Capital Advisors New York $366M AUM 474.6% 1-Year Est. Return
CC
Commodore Capital New York $1.68B AUM 375.52% 1-Year Est. Return
NMC
NEA Management Company Timonium, Maryland $1.59B AUM 234.06% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return
KCM
Kalehua Capital Management Dallas, Texas $174M AUM
SSC
Spruce Street Capital New York $510M AUM
Blackstone Inc
Blackstone Inc New York $32.9B AUM 23.66% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Two Sigma Investments's LONA Position: Q2 2026 in Review

Two Sigma Investments held its LeonaBio Inc (LONA) position steady in Q2 2026 at 13,276 shares worth $122K. The position accounts for ﹤0.01% of the portfolio, ranked #4865.

Two Sigma Investments first reported a position in LONA in Q2 2021 and has held it in 17 quarters since. The position peaked at $2.11M in Q4 2021. 44 funds tracked by Wall St. Rank hold LONA as of Q2 2026.

  • Two Sigma Investments held 13,276 shares of LeonaBio Inc worth $122K as of Q2 2026.
  • Two Sigma Investments left its LeonaBio Inc share count unchanged in Q2 2026.
  • LeonaBio Inc made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #4865 holding.
  • Two Sigma Investments first reported a position in LeonaBio Inc in Q2 2021 and has held it in 17 quarters since.
  • Two Sigma Investments's LeonaBio Inc position peaked at $2.11M in Q4 2021.
  • 44 funds tracked by Wall St. Rank held LeonaBio Inc as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.