Two Sigma Investments
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Two Sigma Investments’s Werewolf Therapeutics HOWL Stock Holding History

Two Sigma Investments’s Portfolio HOWL Stock Details HOWL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$9.82K Buy
+27,300
New +$16.6K ﹤0.01% 5005
2025
Q4 		– Sell
-20,139
Closed -$39.7K – 4208
2025
Q3 		$39.7K Sell
20,139
-25,283
-56% -$34.6K ﹤0.01% 3556
2025
Q2 		$49.5K Sell
45,422
-12,710
-22% -$13.1K ﹤0.01% 3062
2025
Q1 		$56.5K Sell
58,132
-35,308
-38% -$46.2K ﹤0.01% 3032
2024
Q4 		$138K Sell
93,440
-87,168
-48% -$178K ﹤0.01% 2930
2024
Q3 		$383K Sell
180,608
-38,758
-18% -$88.2K ﹤0.01% 2580
2024
Q2 		$535K Buy
219,366
+34,307
+19% +$165K ﹤0.01% 2338
2024
Q1 		$1.2M Buy
185,059
+38,323
+26% +$223K ﹤0.01% 1840
2023
Q4 		$566K Buy
+146,736
New +$375K ﹤0.01% 2396
2023
Q3 		– Sell
-16,537
Closed -$50.4K – 3059
2023
Q2 		$50.4K Sell
16,537
-9,300
-36% -$26.2K ﹤0.01% 2829
2023
Q1 		$67.2K Sell
25,837
-1,348
-5% -$4.02K ﹤0.01% 2717
2022
Q4 		$55.7K Buy
+27,185
New +$71.1K ﹤0.01% 2578
2022
Q2 		– Sell
-15,180
Closed -$67K – 2699
2022
Q1 		$67K Sell
15,180
-6,854
-31% -$48K ﹤0.01% 2468
2021
Q4 		$262K Buy
+22,034
New +$333K ﹤0.01% 3738

Other funds holding HOWL

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $80.2B AUM 51.53% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
LCM
Lynx1 Capital Management San Juan, Puerto Rico $866M AUM 231.68% 1-Year Est. Return
SFM
Sphera Funds Management Tel Aviv, Israel $767M AUM 119.71% 1-Year Est. Return
DF
DC Funds Mclean, Virginia $1.25M AUM 26.51% 1-Year Est. Return
VA
Verdad Advisers Boston, Massachusetts $104M AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
Bank of America
Bank of America Charlotte, North Carolina $1.55T AUM 33.47% 1-Year Est. Return

Two Sigma Investments's HOWL Position: Q2 2026 in Review

Two Sigma Investments opened a new position in Werewolf Therapeutics (HOWL) in Q2 2026: 27,300 shares worth $9.82K. The stake represents ﹤0.01% of the portfolio and ranks #5005 among its holdings. This is a return to the name: Two Sigma Investments previously reported a position in HOWL as recently as Q3 2025.

Two Sigma Investments first reported a position in HOWL in Q4 2021 and has held it in 14 quarters since. The position peaked at $1.2M in Q1 2024. 45 funds tracked by Wall St. Rank hold HOWL as of Q2 2026.

  • Two Sigma Investments held 27,300 shares of Werewolf Therapeutics worth $9.82K as of Q2 2026.
  • Werewolf Therapeutics was a new Two Sigma Investments position in Q2 2026.
  • Werewolf Therapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #5005 holding.
  • Two Sigma Investments first reported a position in Werewolf Therapeutics in Q4 2021 and has held it in 14 quarters since.
  • Two Sigma Investments's Werewolf Therapeutics position peaked at $1.2M in Q1 2024.
  • 45 funds tracked by Wall St. Rank held Werewolf Therapeutics as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.