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Werewolf Therapeutics

51 hedge funds and large institutions have $9.34M invested in Werewolf Therapeutics in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 14 increasing their positions, 17 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

15.8% less ownership

Funds ownership: 46.16%30.36% (-16%)

18% less repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 17

18% less funds holding

Funds holding: 6251 (-11)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

53% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 15

78% less capital invested

Capital invested by funds: $41.6M → $9.34M (-$32.2M)

Holders
51
Holders Change
-11
Holders Change %
-17.74%
% of All Funds
0.62%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
7
Increased
14
Reduced
17
Closed
15
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$4.23M
Vanguard Group
2
Vanguard Group
Pennsylvania
$893K
MB
3
MPM BioImpact
Massachusetts
$884K -$1.23M -1,015,253 -42%
Bank of America
4
Bank of America
North Carolina
$467K -$1.33M -1,092,742 -60%
Renaissance Technologies
5
Renaissance Technologies
New York
$429K +$270K +221,766 +49%
LCM
6
Lynx1 Capital Management
Puerto Rico
$416K +$797K +655,926 New
SFM
7
Sphera Funds Management
Israel
$397K
DF
8
DC Funds
Virginia
$373K
Geode Capital Management
9
Geode Capital Management
Massachusetts
$213K +$6.2K +5,099 +2%
Millennium Management
10
Millennium Management
New York
$152K -$93.5K -76,944 -24%
Alyeska Investment Group
11
Alyeska Investment Group
Illinois
$149K
Jane Street
12
Jane Street
New York
$99.7K -$135K -111,255 -41%
State Street
13
State Street
Massachusetts
$75.5K
BlackRock
14
BlackRock
New York
$64.4K +$389 +320 +0.3%
Susquehanna International Group
15
Susquehanna International Group
Pennsylvania
$63.2K +$8.25K +6,788 +7%
Northern Trust
16
Northern Trust
Illinois
$55K +$25.6K +21,015 +32%
BCM
17
Bridgeway Capital Management
Texas
$48.8K -$30.4K -25,000 -25%
UBS Group
18
UBS Group
Switzerland
$38.4K +$58.3K +47,932 +375%
Vontobel Holding
19
Vontobel Holding
Switzerland
$38K +$29.2K +24,003 +67%
RIA
20
Regal Investment Advisors
Michigan
$33.3K +$30.9K +25,389 +93%
Edgewood Management
21
Edgewood Management
Connecticut
$31.7K
Morgan Stanley
22
Morgan Stanley
New York
$29.1K +$32.5K +26,750 +139%
Goldman Sachs
23
Goldman Sachs
New York
$21.6K -$31.9K -26,268 -44%
Simplex Trading
24
Simplex Trading
Illinois
$15.3K +$10.2K +8,418 +54%
C
25
Certuity
Florida
$9.5K

HOWL Hedge Fund Activity: Q4 2025 in Review

51 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Werewolf Therapeutics (HOWL) for Q4 2025, worth a combined $9.34M — down 78% from $41.6M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of HOWL and 7 opened new positions — a net loss of 8 holders — while 17 trimmed existing stakes and 14 added.

The largest buyer was Lynx1 Capital Management, opening a new position worth an estimated $797K. The largest seller was Bank of America, cutting an estimated $1.33M.

  • 51 institutional investors held Werewolf Therapeutics (HOWL) as of Q4 2025, down from 62 in Q3 2025.
  • Funds reported $9.34M of Werewolf Therapeutics stock for Q4 2025, down 78% quarter-over-quarter.
  • 7 funds opened new Werewolf Therapeutics positions in Q4 2025 and 15 closed out, a net change of -8 holders.
  • The largest Werewolf Therapeutics buyer in Q4 2025 was Lynx1 Capital Management, an estimated $797K added.
  • The largest Werewolf Therapeutics seller in Q4 2025 was Bank of America, an estimated $1.33M sold.

Based on aggregated 13F filings for Q4 2025.