We are live on ! Find out more
HOWL icon

Werewolf Therapeutics

62 hedge funds and large institutions have $41.6M invested in Werewolf Therapeutics in 2025 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 10 increasing their positions, 21 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

71% more capital invested

Capital invested by funds: $24.3M → $41.6M (+$17.3M)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

3.57% less ownership

Funds ownership: 49.73%46.16% (-3.6%)

5% less funds holding

Funds holding: 6562 (-3)

20% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 10

52% less repeat investments, than reductions

Existing positions increased: 10 | Existing positions reduced: 21

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $2K

Holders
62
Holders Change
-3
Holders Change %
-4.62%
% of All Funds
0.81%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
8
Increased
10
Reduced
21
Closed
10
Calls
Puts
$2K
Net Calls
-$2K
Net Calls Change
+$6K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$13.2M
MAM
2
MPM Asset Management
Massachusetts
$8.49M
MB
3
MPM BioImpact
Massachusetts
$4.75M
Bank of America
4
Bank of America
North Carolina
$3.61M -$409K -298,732 -14%
Vanguard Group
5
Vanguard Group
Pennsylvania
$2.77M +$150K +109,796 +8%
SFM
6
Sphera Funds Management
Israel
$1.23M
DF
7
DC Funds
Virginia
$1.16M
Renaissance Technologies
8
Renaissance Technologies
New York
$898K +$191K +139,700 +44%
PHS
9
PFM Health Sciences
California
$790K
Geode Capital Management
10
Geode Capital Management
Massachusetts
$652K +$3.88K +2,832 +0.9%
Millennium Management
11
Millennium Management
New York
$625K -$520K -379,642 -54%
Jane Street
12
Jane Street
New York
$529K -$146K -106,362 -28%
Alyeska Investment Group
13
Alyeska Investment Group
Illinois
$464K
Citadel Advisors
14
Citadel Advisors
Florida
$304K +$212K +154,534 New
State Street
15
State Street
Massachusetts
$235K
BCM
16
Bridgeway Capital Management
Texas
$201K
BlackRock
17
BlackRock
New York
$200K -$357K -260,660 -72%
Susquehanna International Group
18
Susquehanna International Group
Pennsylvania
$183K +$18.4K +13,439 +17%
Northern Trust
19
Northern Trust
Illinois
$130K
Goldman Sachs
20
Goldman Sachs
New York
$119K -$229K -167,101 -73%
Edgewood Management
21
Edgewood Management
Connecticut
$98.5K
CSS
22
Cubist Systematic Strategies
Connecticut
$92K +$64K +46,711 New
HF
23
HRT Financial
New York
$78K -$3.59K -2,621 -6%
Vontobel Holding
24
Vontobel Holding
Switzerland
$70.9K -$5.48K -4,000 -10%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$68.2K -$30.1K -22,000 -39%

HOWL Hedge Fund Activity: Q3 2025 in Review

62 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Werewolf Therapeutics (HOWL) for Q3 2025, worth a combined $41.6M — up 71% from $24.3M a quarter earlier.

Sellers outnumbered buyers: 10 funds closed out of HOWL and 8 opened new positions — a net loss of 2 holders — while 21 trimmed existing stakes and 10 added.

The largest buyer was Citadel Advisors, opening a new position worth an estimated $212K. The largest seller was Millennium Management, cutting an estimated $520K.

  • 62 institutional investors held Werewolf Therapeutics (HOWL) as of Q3 2025, down from 65 in Q2 2025.
  • Funds reported $41.6M of Werewolf Therapeutics stock for Q3 2025, up 71% quarter-over-quarter.
  • 8 funds opened new Werewolf Therapeutics positions in Q3 2025 and 10 closed out, a net change of -2 holders.
  • The largest Werewolf Therapeutics buyer in Q3 2025 was Citadel Advisors, an estimated $212K added.
  • The largest Werewolf Therapeutics seller in Q3 2025 was Millennium Management, an estimated $520K sold.

Based on aggregated 13F filings for Q3 2025.