Two Sigma Investments

Two Sigma Investments’s Biomea Fusion BMEA Stock Holding History

Two Sigma Investments’s Portfolio BMEA Stock Details BMEA Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$595K	Sell	388,696 -34,773	-8%	-$45.7K	﹤0.01%	3620
2025 Q4	$525K	Sell	423,469 -139,499	-25%	-$195K	﹤0.01%	3279
2025 Q3	$1.14M	Buy	562,968 +213,321	+61%	+$391K	﹤0.01%	2494
2025 Q2	$629K	Sell	349,647 -122,712	-26%	-$236K	﹤0.01%	2479
2025 Q1	$1.01M	Sell	472,359 -87,571	-16%	-$298K	﹤0.01%	2171
2024 Q4	$2.17M	Buy	559,930 +286,049	+104%	+$2.28M	﹤0.01%	1654
2024 Q3	$2.77M	Sell	273,881 -56,793	-17%	-$369K	0.01%	1474
2024 Q2	$1.49M	Buy	330,674 +297,273	+890%	+$3.02M	﹤0.01%	1755
2024 Q1	$499K	Sell	33,401 -104,837	-76%	-$1.73M	﹤0.01%	2335
2023 Q4	$2.01M	Sell	138,238 -278,854	-67%	-$3.39M	﹤0.01%	1546
2023 Q3	$5.74M	Buy	417,092 +331,097	+385%	+$5.97M	0.02%	827
2023 Q2	$1.89M	Buy	85,995 +66,079	+332%	+$2.07M	﹤0.01%	1472
2023 Q1	$618K	Buy	19,916 +3,792	+24%	+$47.1K	﹤0.01%	2109
2022 Q4	$136K	Buy	+16,124	New	+$138K	﹤0.01%	2463
2022 Q1	–	Sell	-17,010	Closed	-$127K	–	2816
2021 Q4	$127K	Buy	+17,010	New	+$180K	﹤0.01%	4017

Other funds holding BMEA

Fidelity Investments

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Aisling Capital Management New York $476M AUM 128.63% 1-Year Est. Return

Renaissance Technologies

Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return

Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Citadel Advisors

Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

Mariner Overland Park, Kansas $85.7B AUM 24.21% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Susquehanna International Group

Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return

Fideuram - Intesa Sanpaolo Private Banking Turin $2.85B AUM